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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IL10
All Species:
16.97
Human Site:
T24
Identified Species:
46.67
UniProt:
P22301
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22301
NP_000563.1
178
20517
T24
R
A
S
P
G
Q
G
T
Q
S
E
N
S
C
T
Chimpanzee
Pan troglodytes
A2T6Z6
178
20539
T24
R
A
S
P
G
Q
G
T
Q
S
E
N
S
C
T
Rhesus Macaque
Macaca mulatta
P51496
178
20538
T24
R
A
S
P
G
Q
G
T
Q
S
E
N
S
C
T
Dog
Lupus familis
XP_855560
179
20590
T25
G
A
S
R
H
Q
S
T
L
P
E
D
D
C
T
Cat
Felis silvestris
Mouse
Mus musculus
P18893
178
20655
S24
R
I
S
R
G
Q
Y
S
R
E
D
N
N
C
T
Rat
Rattus norvegicus
P29456
178
20407
I24
K
T
S
K
G
H
S
I
R
G
D
N
N
C
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508589
271
30771
S24
E
P
A
W
G
Q
N
S
P
S
A
E
N
C
V
Chicken
Gallus gallus
Q6A2H4
175
20495
P24
L
P
A
H
C
L
E
P
T
C
L
H
F
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001018621
180
21011
V25
D
C
A
Q
S
R
R
V
E
C
K
T
D
C
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
95.5
80.4
N.A.
71.9
73.5
N.A.
36.9
44.9
N.A.
29.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
98.3
87.7
N.A.
86.5
87
N.A.
48.7
60.6
N.A.
54.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
46.6
N.A.
46.6
33.3
N.A.
26.6
0
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
53.3
N.A.
73.3
60
N.A.
46.6
13.3
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
45
34
0
0
0
0
0
0
0
12
0
0
0
0
% A
% Cys:
0
12
0
0
12
0
0
0
0
23
0
0
0
89
12
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
23
12
23
0
0
% D
% Glu:
12
0
0
0
0
0
12
0
12
12
45
12
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
12
0
0
0
67
0
34
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
12
12
12
0
0
0
0
0
12
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
12
0
0
0
0
0
0
12
0
0
0
0
% K
% Leu:
12
0
0
0
0
12
0
0
12
0
12
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
56
34
0
0
% N
% Pro:
0
23
0
34
0
0
0
12
12
12
0
0
0
0
0
% P
% Gln:
0
0
0
12
0
67
0
0
34
0
0
0
0
0
0
% Q
% Arg:
45
0
0
23
0
12
12
0
23
0
0
0
0
0
0
% R
% Ser:
0
0
67
0
12
0
23
23
0
45
0
0
34
12
0
% S
% Thr:
0
12
0
0
0
0
0
45
12
0
0
12
0
0
67
% T
% Val:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
12
% V
% Trp:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _