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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
16.67
Human Site:
S430
Identified Species:
28.21
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
S430
A
R
L
R
E
A
L
S
D
V
V
G
D
H
N
Chimpanzee
Pan troglodytes
XP_516857
643
72946
G459
E
N
Y
R
E
A
L
G
D
V
V
G
D
Y
N
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
S430
A
R
L
R
E
A
L
S
D
V
V
G
D
H
N
Dog
Lupus familis
XP_546946
611
67308
S427
A
R
L
R
E
A
M
S
D
V
V
G
D
H
N
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
S430
T
H
L
R
D
A
M
S
A
V
V
G
D
H
N
Rat
Rattus norvegicus
P37136
614
68178
S430
A
H
L
R
D
A
M
S
A
V
V
G
D
H
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
G418
D
N
Y
R
V
A
M
G
D
I
I
G
D
Y
N
Chicken
Gallus gallus
P36196
767
83002
D585
V
K
N
R
E
A
L
D
D
I
V
G
D
H
N
Frog
Xenopus laevis
NP_001121332
600
68177
D416
I
K
N
R
E
A
M
D
Q
L
V
G
D
H
N
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
D417
Q
K
N
R
D
A
M
D
D
I
V
G
D
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
G470
Y
Q
N
Q
Q
Q
I
G
R
A
V
G
D
H
F
Honey Bee
Apis mellifera
XP_393751
657
73886
D456
H
A
N
R
D
A
L
D
K
I
V
G
D
Y
Q
Nematode Worm
Caenorhab. elegans
P38433
620
71415
D420
R
D
W
I
N
A
M
D
K
M
L
G
D
Y
H
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
N354
I
M
L
G
S
N
L
N
E
A
Y
F
F
I
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
66.6
100
93.3
N.A.
66.6
73.3
N.A.
40
66.6
53.3
46.6
N.A.
26.6
40
20
13.3
P-Site Similarity:
100
73.3
100
100
N.A.
80
86.6
N.A.
66.6
80
73.3
73.3
N.A.
53.3
60
53.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
8
0
0
0
86
0
0
15
15
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
29
0
0
36
50
0
0
0
93
0
0
% D
% Glu:
8
0
0
0
43
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
8
% F
% Gly:
0
0
0
8
0
0
0
22
0
0
0
93
0
0
0
% G
% His:
8
15
0
0
0
0
0
0
0
0
0
0
0
58
8
% H
% Ile:
15
0
0
8
0
0
8
0
0
29
8
0
0
8
8
% I
% Lys:
0
22
0
0
0
0
0
0
15
0
0
0
0
0
0
% K
% Leu:
0
0
43
0
0
0
43
0
0
8
8
0
0
0
0
% L
% Met:
0
8
0
0
0
0
50
0
0
8
0
0
0
0
0
% M
% Asn:
0
15
36
0
8
8
0
8
0
0
0
0
0
0
72
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
8
0
8
8
8
0
0
8
0
0
0
0
8
8
% Q
% Arg:
8
22
0
79
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
0
0
36
0
0
0
0
0
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
8
0
0
0
0
43
79
0
0
0
0
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
15
0
0
0
0
0
0
0
8
0
0
29
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _