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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
24.85
Human Site:
S88
Identified Species:
42.05
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
S88
P
E
P
K
Q
P
W
S
G
V
V
D
A
T
T
Chimpanzee
Pan troglodytes
XP_516857
643
72946
W121
K
P
Q
S
L
T
K
W
S
D
I
W
N
A
T
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
S88
P
E
P
K
Q
P
W
S
G
V
V
D
A
T
T
Dog
Lupus familis
XP_546946
611
67308
S85
P
E
P
K
R
P
W
S
G
V
L
D
A
T
A
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
S88
P
E
P
K
R
P
W
S
G
V
L
D
A
T
T
Rat
Rattus norvegicus
P37136
614
68178
S88
P
E
P
K
R
P
W
S
G
I
L
D
A
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
W80
K
P
Q
P
R
N
R
W
S
N
T
W
D
A
T
Chicken
Gallus gallus
P36196
767
83002
W81
P
L
P
I
P
T
P
W
T
G
I
R
D
A
D
Frog
Xenopus laevis
NP_001121332
600
68177
T78
S
E
P
K
K
P
W
T
D
V
W
D
A
T
A
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
N79
A
E
P
K
K
P
W
N
N
V
F
E
A
K
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
H92
P
V
P
A
E
P
W
H
G
V
L
D
A
T
G
Honey Bee
Apis mellifera
XP_393751
657
73886
S119
P
R
P
A
E
R
W
S
G
I
L
N
A
T
T
Nematode Worm
Caenorhab. elegans
P38433
620
71415
R70
P
K
P
K
Q
P
W
R
I
P
L
N
A
T
T
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
V43
L
G
K
R
L
T
T
V
A
V
G
A
P
N
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
6.6
100
80
N.A.
86.6
80
N.A.
6.6
13.3
60
46.6
N.A.
60
53.3
60
6.6
P-Site Similarity:
100
13.3
100
93.3
N.A.
100
100
N.A.
13.3
20
73.3
66.6
N.A.
73.3
80
80
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
15
0
0
0
0
8
0
0
8
72
22
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
0
50
15
0
8
% D
% Glu:
0
50
0
0
15
0
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
0
0
50
8
8
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
8
15
15
0
0
0
0
% I
% Lys:
15
8
8
58
15
0
8
0
0
0
0
0
0
8
0
% K
% Leu:
8
8
0
0
15
0
0
0
0
0
43
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
8
8
0
15
8
8
0
% N
% Pro:
65
15
79
8
8
65
8
0
0
8
0
0
8
0
0
% P
% Gln:
0
0
15
0
22
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
8
29
8
8
8
0
0
0
8
0
0
8
% R
% Ser:
8
0
0
8
0
0
0
43
15
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
22
8
8
8
0
8
0
0
65
58
% T
% Val:
0
8
0
0
0
0
0
8
0
58
15
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
72
22
0
0
8
15
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _