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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
23.94
Human Site:
Y101
Identified Species:
40.51
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
Y101
T
T
F
Q
S
V
C
Y
Q
Y
V
D
T
L
Y
Chimpanzee
Pan troglodytes
XP_516857
643
72946
C134
A
T
K
Y
A
N
S
C
C
Q
N
I
D
Q
S
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
Y101
T
T
F
Q
S
V
C
Y
Q
Y
V
D
T
L
Y
Dog
Lupus familis
XP_546946
611
67308
Y98
T
A
F
Q
S
V
C
Y
Q
Y
V
D
T
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
Y101
T
T
F
Q
N
V
C
Y
Q
Y
V
D
T
L
Y
Rat
Rattus norvegicus
P37136
614
68178
Y101
T
T
F
Q
N
V
C
Y
Q
Y
V
D
T
L
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
C93
A
T
K
Y
S
N
S
C
Y
Q
N
V
D
Q
S
Chicken
Gallus gallus
P36196
767
83002
C94
A
D
S
Q
P
F
A
C
Y
Q
M
V
D
T
T
Frog
Xenopus laevis
NP_001121332
600
68177
Y91
T
A
Y
P
D
A
C
Y
Q
Y
F
D
T
L
Y
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
Y92
K
E
F
S
N
A
C
Y
Q
F
V
D
T
S
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
V105
T
G
L
S
A
T
C
V
Q
E
R
Y
E
Y
F
Honey Bee
Apis mellifera
XP_393751
657
73886
V132
T
T
L
P
N
S
C
V
Q
I
L
D
T
V
F
Nematode Worm
Caenorhab. elegans
P38433
620
71415
I83
T
T
P
P
N
S
C
I
Q
S
E
D
T
Y
F
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
L56
N
R
Q
V
D
A
F
L
G
I
P
Y
A
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
93.3
N.A.
13.3
6.6
60
53.3
N.A.
20
40
40
0
P-Site Similarity:
100
13.3
100
93.3
N.A.
100
100
N.A.
13.3
13.3
66.6
66.6
N.A.
33.3
66.6
53.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
0
0
15
22
8
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
72
22
8
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
15
0
0
0
0
0
0
65
22
0
0
% D
% Glu:
0
8
0
0
0
0
0
0
0
8
8
0
8
8
0
% E
% Phe:
0
0
43
0
0
8
8
0
0
8
8
0
0
0
22
% F
% Gly:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
8
0
15
0
8
0
0
0
% I
% Lys:
8
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
0
0
8
0
0
8
0
0
43
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
8
0
0
0
36
15
0
0
0
0
15
0
0
0
0
% N
% Pro:
0
0
8
22
8
0
0
0
0
0
8
0
0
0
8
% P
% Gln:
0
0
8
43
0
0
0
0
72
22
0
0
0
15
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
8
15
29
15
15
0
0
8
0
0
0
8
15
% S
% Thr:
65
58
0
0
0
8
0
0
0
0
0
0
65
8
8
% T
% Val:
0
0
0
8
0
36
0
15
0
0
43
15
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
15
0
0
0
50
15
43
0
15
0
15
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _