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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
25.76
Human Site:
Y108
Identified Species:
43.59
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
Y108
Y
Q
Y
V
D
T
L
Y
P
G
F
E
G
T
E
Chimpanzee
Pan troglodytes
XP_516857
643
72946
S141
C
C
Q
N
I
D
Q
S
F
P
G
F
H
G
S
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
Y108
Y
Q
Y
V
D
T
L
Y
P
G
F
E
G
T
E
Dog
Lupus familis
XP_546946
611
67308
Y105
Y
Q
Y
V
D
T
L
Y
P
G
F
E
G
T
E
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
Y108
Y
Q
Y
V
D
T
L
Y
P
G
F
E
G
T
E
Rat
Rattus norvegicus
P37136
614
68178
Y108
Y
Q
Y
V
D
T
L
Y
P
G
F
E
G
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
S100
C
Y
Q
N
V
D
Q
S
F
P
G
F
P
G
S
Chicken
Gallus gallus
P36196
767
83002
T101
C
Y
Q
M
V
D
T
T
F
P
G
F
Q
G
S
Frog
Xenopus laevis
NP_001121332
600
68177
Y98
Y
Q
Y
F
D
T
L
Y
P
G
F
P
G
M
E
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
Y99
Y
Q
F
V
D
T
S
Y
P
G
F
P
G
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
F112
V
Q
E
R
Y
E
Y
F
P
G
F
S
G
E
E
Honey Bee
Apis mellifera
XP_393751
657
73886
F139
V
Q
I
L
D
T
V
F
G
E
F
A
G
A
T
Nematode Worm
Caenorhab. elegans
P38433
620
71415
F90
I
Q
S
E
D
T
Y
F
G
D
F
Y
G
S
T
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
P63
L
G
I
P
Y
A
E
P
P
V
D
D
L
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
0
0
80
73.3
N.A.
40
33.3
33.3
6.6
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
0
6.6
80
80
N.A.
46.6
53.3
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
8
0
8
0
% A
% Cys:
22
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
65
22
0
0
0
8
8
8
0
0
0
% D
% Glu:
0
0
8
8
0
8
8
0
0
8
0
36
0
8
58
% E
% Phe:
0
0
8
8
0
0
0
22
22
0
72
22
0
0
8
% F
% Gly:
0
8
0
0
0
0
0
0
15
58
22
0
72
22
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
15
0
8
0
0
0
0
0
0
0
0
8
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
8
0
0
43
0
0
0
0
0
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
8
0
0
0
8
65
22
0
15
8
0
0
% P
% Gln:
0
72
22
0
0
0
15
0
0
0
0
0
8
0
0
% Q
% Arg:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
0
0
8
0
0
0
8
15
0
0
0
8
0
8
22
% S
% Thr:
0
0
0
0
0
65
8
8
0
0
0
0
0
36
15
% T
% Val:
15
0
0
43
15
0
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
50
15
43
0
15
0
15
50
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _