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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACHE
All Species:
24.85
Human Site:
Y534
Identified Species:
42.05
UniProt:
P22303
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22303
NP_000656.1
614
67796
Y534
K
A
P
Q
W
P
P
Y
T
A
G
A
Q
Q
Y
Chimpanzee
Pan troglodytes
XP_516857
643
72946
F562
N
S
T
R
W
P
V
F
K
S
T
E
Q
K
Y
Rhesus Macaque
Macaca mulatta
NP_001121560
614
67754
Y534
K
A
P
Q
W
P
P
Y
T
A
G
A
Q
Q
Y
Dog
Lupus familis
XP_546946
611
67308
Y531
K
V
P
Q
W
P
P
Y
T
A
G
A
Q
Q
Y
Cat
Felis silvestris
Mouse
Mus musculus
P21836
614
68150
Y534
K
S
P
Q
W
P
P
Y
T
T
A
A
Q
Q
Y
Rat
Rattus norvegicus
P37136
614
68178
Y534
K
S
P
R
W
P
P
Y
T
T
A
A
Q
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505841
602
68511
F521
N
G
T
R
W
P
I
F
K
S
T
E
Q
K
Y
Chicken
Gallus gallus
P36196
767
83002
Y687
G
G
P
R
W
P
P
Y
T
P
S
G
Q
R
Y
Frog
Xenopus laevis
NP_001121332
600
68177
Y520
R
Q
Q
R
W
P
L
Y
T
A
S
E
Q
R
Y
Zebra Danio
Brachydanio rerio
Q9DDE3
634
71980
F554
S
R
R
R
W
P
Q
F
S
A
N
E
Q
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P07140
649
71767
E573
E
W
P
N
F
S
K
E
D
P
V
Y
Y
I
F
Honey Bee
Apis mellifera
XP_393751
657
73886
H562
T
Q
A
Y
W
P
P
H
T
A
A
K
K
E
Y
Nematode Worm
Caenorhab. elegans
P38433
620
71415
Y527
T
Q
D
V
W
P
K
Y
N
S
V
S
M
E
Y
Sea Urchin
Strong. purpuratus
XP_782113
508
56946
N444
Y
S
Y
A
S
A
N
N
K
V
Y
Y
Y
R
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.9
99.5
92.8
N.A.
88.4
88.5
N.A.
50.6
47.9
59.6
60
N.A.
34.3
39.8
41.2
37.7
Protein Similarity:
100
66.8
99.6
96
N.A.
93
93.6
N.A.
68.2
58
73.4
73.6
N.A.
51.4
56.9
56.9
51.6
P-Site Identity:
100
26.6
100
93.3
N.A.
80
73.3
N.A.
26.6
53.3
46.6
26.6
N.A.
6.6
40
26.6
0
P-Site Similarity:
100
60
100
93.3
N.A.
86.6
86.6
N.A.
53.3
66.6
66.6
60
N.A.
26.6
60
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
8
8
0
8
0
0
0
43
22
36
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
0
8
0
0
0
29
0
15
0
% E
% Phe:
0
0
0
0
8
0
0
22
0
0
0
0
0
0
15
% F
% Gly:
8
15
0
0
0
0
0
0
0
0
22
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
36
0
0
0
0
0
15
0
22
0
0
8
8
22
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
15
0
0
8
0
0
8
8
8
0
8
0
0
0
0
% N
% Pro:
0
0
50
0
0
86
50
0
0
15
0
0
0
0
0
% P
% Gln:
0
22
8
29
0
0
8
0
0
0
0
0
72
36
0
% Q
% Arg:
8
8
8
43
0
0
0
0
0
0
0
0
0
22
0
% R
% Ser:
8
29
0
0
8
8
0
0
8
22
15
8
0
0
0
% S
% Thr:
15
0
15
0
0
0
0
0
58
15
15
0
0
0
0
% T
% Val:
0
8
0
8
0
0
8
0
0
8
15
0
0
0
0
% V
% Trp:
0
8
0
0
86
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
8
0
0
0
58
0
0
8
15
15
0
79
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _