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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDS
All Species:
10.3
Human Site:
S154
Identified Species:
22.67
UniProt:
P22304
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22304
NP_000193.1
550
61873
S154
D
D
S
P
Y
S
W
S
F
P
P
Y
H
P
S
Chimpanzee
Pan troglodytes
XP_521297
659
72527
P267
D
S
S
H
H
C
V
P
G
I
S
S
N
H
T
Rhesus Macaque
Macaca mulatta
XP_001089323
550
61783
S154
D
D
S
P
Y
S
W
S
F
P
P
Y
H
P
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08890
552
62154
S156
D
D
Y
P
Y
S
W
S
F
P
P
Y
H
P
S
Rat
Rattus norvegicus
P15589
577
62660
T163
D
R
F
L
G
T
P
T
T
N
L
R
D
C
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512557
523
58748
N153
K
D
G
K
L
H
A
N
L
I
C
P
V
D
V
Chicken
Gallus gallus
Q5ZK90
535
61383
G158
E
F
L
L
R
Q
E
G
R
P
K
V
N
L
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
T156
R
Q
E
G
R
P
V
T
D
L
V
G
D
A
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647814
512
58886
R147
S
W
S
A
P
A
F
R
P
R
T
E
Q
F
M
Honey Bee
Apis mellifera
XP_001120439
494
56877
P129
S
N
N
S
D
D
N
P
Y
S
W
S
E
T
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785170
567
64142
A160
P
T
Q
E
Y
K
R
A
K
V
C
K
N
M
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
96.9
N.A.
N.A.
85.6
20.6
N.A.
68.3
23.6
N.A.
21
N.A.
44.5
44.7
N.A.
48.8
Protein Similarity:
100
65.5
98.5
N.A.
N.A.
90.5
36.2
N.A.
78.3
40.9
N.A.
39.8
N.A.
60.9
61.2
N.A.
65.2
P-Site Identity:
100
13.3
100
N.A.
N.A.
93.3
6.6
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
0
N.A.
6.6
P-Site Similarity:
100
33.3
100
N.A.
N.A.
93.3
20
N.A.
13.3
26.6
N.A.
13.3
N.A.
20
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
10
10
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
19
0
0
10
0
% C
% Asp:
46
37
0
0
10
10
0
0
10
0
0
0
19
10
10
% D
% Glu:
10
0
10
10
0
0
10
0
0
0
0
10
10
0
0
% E
% Phe:
0
10
10
0
0
0
10
0
28
0
0
0
0
10
0
% F
% Gly:
0
0
10
10
10
0
0
10
10
0
0
10
0
0
0
% G
% His:
0
0
0
10
10
10
0
0
0
0
0
0
28
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
10
0
0
10
0
10
10
0
0
10
% K
% Leu:
0
0
10
19
10
0
0
0
10
10
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% M
% Asn:
0
10
10
0
0
0
10
10
0
10
0
0
28
0
0
% N
% Pro:
10
0
0
28
10
10
10
19
10
37
28
10
0
28
10
% P
% Gln:
0
10
10
0
0
10
0
0
0
0
0
0
10
0
0
% Q
% Arg:
10
10
0
0
19
0
10
10
10
10
0
10
0
0
0
% R
% Ser:
19
10
37
10
0
28
0
28
0
10
10
19
0
0
37
% S
% Thr:
0
10
0
0
0
10
0
19
10
0
10
0
0
10
19
% T
% Val:
0
0
0
0
0
0
19
0
0
10
10
10
10
0
10
% V
% Trp:
0
10
0
0
0
0
28
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
37
0
0
0
10
0
0
28
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _