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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDS
All Species:
14.24
Human Site:
S50
Identified Species:
31.33
UniProt:
P22304
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22304
NP_000193.1
550
61873
S50
I
V
D
D
L
R
P
S
L
G
C
Y
G
D
K
Chimpanzee
Pan troglodytes
XP_521297
659
72527
S163
I
V
D
D
L
R
P
S
L
G
C
Y
G
D
K
Rhesus Macaque
Macaca mulatta
XP_001089323
550
61783
S50
I
V
D
D
L
R
P
S
L
G
C
Y
G
D
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08890
552
62154
S52
I
V
D
D
L
R
P
S
L
G
C
Y
G
D
K
Rat
Rattus norvegicus
P15589
577
62660
R56
L
R
T
P
H
I
D
R
L
A
L
E
G
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512557
523
58748
G50
G
W
S
L
L
G
A
G
L
A
Q
A
V
C
A
Chicken
Gallus gallus
Q5ZK90
535
61383
T55
T
F
Y
P
G
N
Q
T
V
D
L
P
F
I
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
L52
P
G
N
K
V
V
Q
L
P
Y
I
N
Y
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647814
512
58886
D44
P
V
I
G
A
Y
G
D
T
L
A
S
T
P
Y
Honey Bee
Apis mellifera
XP_001120439
494
56877
L26
L
L
I
I
V
D
D
L
R
T
A
L
G
C
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785170
567
64142
N55
G
G
P
I
L
S
P
N
I
D
N
L
A
A
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
96.9
N.A.
N.A.
85.6
20.6
N.A.
68.3
23.6
N.A.
21
N.A.
44.5
44.7
N.A.
48.8
Protein Similarity:
100
65.5
98.5
N.A.
N.A.
90.5
36.2
N.A.
78.3
40.9
N.A.
39.8
N.A.
60.9
61.2
N.A.
65.2
P-Site Identity:
100
100
100
N.A.
N.A.
100
20
N.A.
13.3
0
N.A.
0
N.A.
6.6
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
100
26.6
N.A.
13.3
13.3
N.A.
20
N.A.
6.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
10
0
0
19
19
10
10
10
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
37
0
0
19
0
% C
% Asp:
0
0
37
37
0
10
19
10
0
19
0
0
0
37
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
19
19
0
10
10
10
10
10
0
37
0
0
55
0
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
37
0
19
19
0
10
0
0
10
0
10
0
0
10
0
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
46
% K
% Leu:
19
10
0
10
55
0
0
19
55
10
19
19
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
10
0
0
10
0
10
0
0
10
10
0
0
10
% N
% Pro:
19
0
10
19
0
0
46
0
10
0
0
10
0
10
0
% P
% Gln:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
10
% Q
% Arg:
0
10
0
0
0
37
0
10
10
0
0
0
0
0
10
% R
% Ser:
0
0
10
0
0
10
0
37
0
0
0
10
0
0
0
% S
% Thr:
10
0
10
0
0
0
0
10
10
10
0
0
10
0
0
% T
% Val:
0
46
0
0
19
10
0
0
10
0
0
0
10
10
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
10
0
37
10
0
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _