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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDS
All Species:
9.7
Human Site:
T146
Identified Species:
21.33
UniProt:
P22304
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22304
NP_000193.1
550
61873
T146
P
G
I
S
S
N
H
T
D
D
S
P
Y
S
W
Chimpanzee
Pan troglodytes
XP_521297
659
72527
D259
P
A
L
G
L
L
Q
D
D
S
S
H
H
C
V
Rhesus Macaque
Macaca mulatta
XP_001089323
550
61783
T146
P
G
I
T
S
N
H
T
D
D
S
P
Y
S
W
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08890
552
62154
S148
P
G
I
S
S
N
H
S
D
D
Y
P
Y
S
W
Rat
Rattus norvegicus
P15589
577
62660
F155
H
H
P
G
R
H
G
F
D
R
F
L
G
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512557
523
58748
G145
E
N
T
K
T
C
R
G
K
D
G
K
L
H
A
Chicken
Gallus gallus
Q5ZK90
535
61383
V150
V
E
A
W
T
R
D
V
E
F
L
L
R
Q
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
L148
T
R
D
V
P
F
L
L
R
Q
E
G
R
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647814
512
58886
L139
N
N
T
D
D
Y
P
L
S
W
S
A
P
A
F
Honey Bee
Apis mellifera
XP_001120439
494
56877
S121
K
V
F
H
P
G
I
S
S
N
N
S
D
D
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785170
567
64142
P152
W
S
V
E
A
W
H
P
P
T
Q
E
Y
K
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
96.9
N.A.
N.A.
85.6
20.6
N.A.
68.3
23.6
N.A.
21
N.A.
44.5
44.7
N.A.
48.8
Protein Similarity:
100
65.5
98.5
N.A.
N.A.
90.5
36.2
N.A.
78.3
40.9
N.A.
39.8
N.A.
60.9
61.2
N.A.
65.2
P-Site Identity:
100
20
93.3
N.A.
N.A.
86.6
6.6
N.A.
6.6
0
N.A.
0
N.A.
6.6
0
N.A.
13.3
P-Site Similarity:
100
33.3
100
N.A.
N.A.
93.3
20
N.A.
13.3
13.3
N.A.
0
N.A.
20
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
0
0
0
10
0
10
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
10
10
10
0
10
10
46
37
0
0
10
10
0
% D
% Glu:
10
10
0
10
0
0
0
0
10
0
10
10
0
0
10
% E
% Phe:
0
0
10
0
0
10
0
10
0
10
10
0
0
0
10
% F
% Gly:
0
28
0
19
0
10
10
10
0
0
10
10
10
0
0
% G
% His:
10
10
0
10
0
10
37
0
0
0
0
10
10
10
0
% H
% Ile:
0
0
28
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
0
0
10
0
0
0
0
10
0
0
10
0
10
0
% K
% Leu:
0
0
10
0
10
10
10
19
0
0
10
19
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
19
0
0
0
28
0
0
0
10
10
0
0
0
10
% N
% Pro:
37
0
10
0
19
0
10
10
10
0
0
28
10
10
10
% P
% Gln:
0
0
0
0
0
0
10
0
0
10
10
0
0
10
0
% Q
% Arg:
0
10
0
0
10
10
10
0
10
10
0
0
19
0
10
% R
% Ser:
0
10
0
19
28
0
0
19
19
10
37
10
0
28
0
% S
% Thr:
10
0
19
10
19
0
0
19
0
10
0
0
0
10
0
% T
% Val:
10
10
10
10
0
0
0
10
0
0
0
0
0
0
19
% V
% Trp:
10
0
0
10
0
10
0
0
0
10
0
0
0
0
28
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
10
0
37
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _