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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDS
All Species:
14.24
Human Site:
Y242
Identified Species:
31.33
UniProt:
P22304
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22304
NP_000193.1
550
61873
Y242
P
K
E
F
Q
K
L
Y
P
L
E
N
I
T
L
Chimpanzee
Pan troglodytes
XP_521297
659
72527
F347
M
K
T
S
A
S
P
F
F
L
A
V
G
Y
H
Rhesus Macaque
Macaca mulatta
XP_001089323
550
61783
Y242
P
K
E
F
Q
K
L
Y
P
L
E
N
I
T
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08890
552
62154
Y244
P
K
E
F
Q
K
L
Y
P
L
E
N
I
T
L
Rat
Rattus norvegicus
P15589
577
62660
F242
H
F
R
P
A
N
C
F
L
M
A
D
F
T
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512557
523
58748
L231
D
P
Q
I
P
I
E
L
P
P
V
A
Y
N
P
Chicken
Gallus gallus
Q5ZK90
535
61383
P243
K
Y
E
A
I
K
I
P
T
W
T
A
L
S
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
S235
K
V
S
Y
N
Q
V
S
V
P
K
W
L
R
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647814
512
58886
R225
H
I
N
F
R
F
P
R
Q
F
L
S
R
F
N
Honey Bee
Apis mellifera
XP_001120439
494
56877
H207
A
V
G
F
Q
K
P
H
I
P
F
K
Y
P
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785170
567
64142
Y242
P
Q
E
Y
R
A
L
Y
P
L
E
E
V
E
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
96.9
N.A.
N.A.
85.6
20.6
N.A.
68.3
23.6
N.A.
21
N.A.
44.5
44.7
N.A.
48.8
Protein Similarity:
100
65.5
98.5
N.A.
N.A.
90.5
36.2
N.A.
78.3
40.9
N.A.
39.8
N.A.
60.9
61.2
N.A.
65.2
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
6.6
N.A.
6.6
13.3
N.A.
0
N.A.
6.6
20
N.A.
46.6
P-Site Similarity:
100
20
100
N.A.
N.A.
100
33.3
N.A.
13.3
33.3
N.A.
33.3
N.A.
20
26.6
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
19
10
0
0
0
0
19
19
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
46
0
0
0
10
0
0
0
37
10
0
10
10
% E
% Phe:
0
10
0
46
0
10
0
19
10
10
10
0
10
10
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
19
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% H
% Ile:
0
10
0
10
10
10
10
0
10
0
0
0
28
0
19
% I
% Lys:
19
37
0
0
0
46
0
0
0
0
10
10
0
0
10
% K
% Leu:
0
0
0
0
0
0
37
10
10
46
10
0
19
0
28
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
10
0
0
0
0
0
28
0
10
10
% N
% Pro:
37
10
0
10
10
0
28
10
46
28
0
0
0
10
10
% P
% Gln:
0
10
10
0
37
10
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
19
0
0
10
0
0
0
0
10
10
0
% R
% Ser:
0
0
10
10
0
10
0
10
0
0
0
10
0
10
0
% S
% Thr:
0
0
10
0
0
0
0
0
10
0
10
0
0
37
0
% T
% Val:
0
19
0
0
0
0
10
0
10
0
10
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% W
% Tyr:
0
10
0
19
0
0
0
37
0
0
0
0
19
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _