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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IDS
All Species:
9.39
Human Site:
Y380
Identified Species:
20.67
UniProt:
P22304
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22304
NP_000193.1
550
61873
Y380
A
G
E
K
L
F
P
Y
L
D
P
F
D
S
A
Chimpanzee
Pan troglodytes
XP_521297
659
72527
Q489
L
S
A
L
D
D
L
Q
L
A
N
S
T
I
I
Rhesus Macaque
Macaca mulatta
XP_001089323
550
61783
Y380
A
G
E
K
L
F
P
Y
L
D
P
F
D
S
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q08890
552
62154
Y382
A
G
Q
K
L
F
P
Y
R
D
P
F
D
P
A
Rat
Rattus norvegicus
P15589
577
62660
I387
L
V
R
W
P
G
V
I
V
P
G
Q
E
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512557
523
58748
P365
S
L
S
E
V
F
S
P
G
V
Q
A
T
E
L
Chicken
Gallus gallus
Q5ZK90
535
61383
L382
Q
N
L
S
G
Y
S
L
L
P
L
L
L
E
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q08CJ7
523
59480
G369
L
A
G
V
P
Q
T
G
G
L
S
G
H
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_647814
512
58886
Y359
F
P
V
A
Q
T
K
Y
Y
H
G
I
T
E
L
Honey Bee
Apis mellifera
XP_001120439
494
56877
S341
L
R
V
P
L
I
I
S
I
P
G
L
T
Y
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785170
567
64142
L380
Q
R
T
K
K
F
P
L
K
N
L
L
K
N
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
62
96.9
N.A.
N.A.
85.6
20.6
N.A.
68.3
23.6
N.A.
21
N.A.
44.5
44.7
N.A.
48.8
Protein Similarity:
100
65.5
98.5
N.A.
N.A.
90.5
36.2
N.A.
78.3
40.9
N.A.
39.8
N.A.
60.9
61.2
N.A.
65.2
P-Site Identity:
100
6.6
100
N.A.
N.A.
80
0
N.A.
6.6
6.6
N.A.
6.6
N.A.
6.6
6.6
N.A.
20
P-Site Similarity:
100
6.6
100
N.A.
N.A.
86.6
13.3
N.A.
26.6
13.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
10
10
10
0
0
0
0
0
10
0
10
0
0
28
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
0
28
0
0
28
0
0
% D
% Glu:
0
0
19
10
0
0
0
0
0
0
0
0
10
28
10
% E
% Phe:
10
0
0
0
0
46
0
0
0
0
0
28
0
0
0
% F
% Gly:
0
28
10
0
10
10
0
10
19
0
28
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% H
% Ile:
0
0
0
0
0
10
10
10
10
0
0
10
0
10
10
% I
% Lys:
0
0
0
37
10
0
10
0
10
0
0
0
10
0
28
% K
% Leu:
37
10
10
10
37
0
10
19
37
10
19
28
10
0
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
0
10
10
0
0
10
0
% N
% Pro:
0
10
0
10
19
0
37
10
0
28
28
0
0
10
0
% P
% Gln:
19
0
10
0
10
10
0
10
0
0
10
10
0
0
0
% Q
% Arg:
0
19
10
0
0
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
10
10
10
0
0
19
10
0
0
10
10
0
28
0
% S
% Thr:
0
0
10
0
0
10
10
0
0
0
0
0
37
0
0
% T
% Val:
0
10
19
10
10
0
10
0
10
10
0
0
0
10
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
37
10
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _