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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBA1 All Species: 31.52
Human Site: Y590 Identified Species: 69.33
UniProt: P22314 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22314 NP_003325.2 1058 117849 Y590 Y M D R R C V Y Y R K P L L E
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001092142 1058 117902 Y590 Y M D R R C V Y Y R K P L L E
Dog Lupus familis XP_538014 1015 112483 F565 R I Y D D D F F Q N L D G V A
Cat Felis silvestris
Mouse Mus musculus Q02053 1058 117790 Y590 Y M D R R C V Y Y R K P L L E
Rat Rattus norvegicus Q5U300 1058 117769 Y590 Y M D R R C V Y Y R K P L L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001080185 1059 117949 Y591 Y M D R R C V Y Y R Q P L L E
Zebra Danio Brachydanio rerio NP_998227 1058 118200 Y590 Y M D R R C V Y Y R K P L L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477310 1191 130740 F725 Y M D R K C I F N R I P L V E
Honey Bee Apis mellifera XP_394434 1049 117087 Y585 Y M D R R C V Y Y R K P L L E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795302 1054 117556 Y588 Y M D R R C V Y Y R K S L L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P22515 1024 114248 F558 Y V D R R C V F Y R K P L L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.6 90.2 N.A. 95.5 96.4 N.A. N.A. N.A. 77.6 78.8 N.A. 54.1 62.2 N.A. 65.2
Protein Similarity: 100 N.A. 99 92.1 N.A. 97.5 98.1 N.A. N.A. N.A. 90.1 90 N.A. 67.3 76.9 N.A. 80.7
P-Site Identity: 100 N.A. 100 0 N.A. 100 100 N.A. N.A. N.A. 93.3 100 N.A. 60 100 N.A. 93.3
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 86.6 100 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 51.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 70.5 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 86.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 91 10 10 10 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 91 % E
% Phe: 0 0 0 0 0 0 10 28 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 10 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 10 0 0 0 0 0 73 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 91 82 0 % L
% Met: 0 82 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 82 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % Q
% Arg: 10 0 0 91 82 0 0 0 0 91 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 82 0 0 0 0 0 0 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 91 0 10 0 0 0 0 73 82 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _