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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR4
All Species:
25.15
Human Site:
S419
Identified Species:
50.3
UniProt:
P22455
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22455
NP_002002.3
802
87954
S419
F
P
L
A
R
Q
F
S
L
E
S
G
S
S
G
Chimpanzee
Pan troglodytes
XP_518127
807
88293
R479
A
L
H
G
R
H
P
R
P
P
A
T
V
Q
K
Rhesus Macaque
Macaca mulatta
XP_001087243
802
87975
S419
F
P
L
A
R
Q
F
S
L
E
S
G
S
S
S
Dog
Lupus familis
XP_546211
858
94257
S476
F
P
L
A
R
Q
F
S
L
E
S
G
S
S
A
Cat
Felis silvestris
Mouse
Mus musculus
Q03142
799
88643
S416
F
P
L
A
R
Q
F
S
L
E
S
R
S
S
G
Rat
Rattus norvegicus
Q498D6
800
88690
S417
F
P
L
A
R
Q
F
S
L
E
S
R
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
V417
F
P
L
K
R
Q
Q
V
S
L
E
S
N
S
S
Frog
Xenopus laevis
Q91743
828
93399
S442
F
P
L
I
R
Q
F
S
L
E
S
S
S
S
G
Zebra Danio
Brachydanio rerio
Q90413
922
103447
S530
F
P
L
R
R
Q
Y
S
V
E
S
N
S
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
P404
P
F
N
E
Y
E
F
P
L
D
S
N
W
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
R571
G
L
V
A
R
K
K
R
V
V
V
S
K
R
P
Sea Urchin
Strong. purpuratus
Q26614
972
110463
S587
P
S
D
K
P
D
I
S
G
P
K
H
L
Y
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.2
97.3
86.7
N.A.
89.7
88.7
N.A.
N.A.
61.5
63.8
56.4
N.A.
35.5
N.A.
30.9
34.2
Protein Similarity:
100
89.7
98.3
88.5
N.A.
92.5
91.6
N.A.
N.A.
72.9
74.6
68.6
N.A.
52.1
N.A.
46.1
49.2
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
40
86.6
73.3
N.A.
20
N.A.
13.3
6.6
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
46.6
86.6
86.6
N.A.
33.3
N.A.
33.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
50
0
0
0
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
9
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
0
0
0
59
9
0
0
9
0
% E
% Phe:
67
9
0
0
0
0
59
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
9
0
0
25
0
0
42
% G
% His:
0
0
9
0
0
9
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
17
0
9
9
0
0
0
9
0
9
0
9
% K
% Leu:
0
17
67
0
0
0
0
0
59
9
0
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
17
9
0
0
% N
% Pro:
17
67
0
0
9
0
9
9
9
17
0
0
0
0
9
% P
% Gln:
0
0
0
0
0
67
9
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
9
84
0
0
17
0
0
0
17
0
9
9
% R
% Ser:
0
9
0
0
0
0
0
67
9
0
67
25
59
67
17
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
9
17
9
9
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
0
0
0
9
0
9
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _