Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FGFR4 All Species: 20.91
Human Site: S783 Identified Species: 41.82
UniProt: P22455 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22455 NP_002002.3 802 87954 S783 S S S D S V F S H D P L P L G
Chimpanzee Pan troglodytes XP_518127 807 88293 S788 S S S D S V F S H D P L P L G
Rhesus Macaque Macaca mulatta XP_001087243 802 87975 S783 S S S D S V F S H D P L P L G
Dog Lupus familis XP_546211 858 94257 C840 S S N D S V F C H D L L P L G
Cat Felis silvestris
Mouse Mus musculus Q03142 799 88643 S780 S S S D S V F S H D P L P L E
Rat Rattus norvegicus Q498D6 800 88690 S781 S S S D S V F S H D P L P L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P18460 806 89712 F783 S S G D D S V F A H D L L P D
Frog Xenopus laevis Q91743 828 93399 F805 S S S D D S V F A P D P V P S
Zebra Danio Brachydanio rerio Q90413 922 103447 F894 S S D N D S V F T H D A L S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 S711 A N L D T P P S T S D E E E D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10656 1040 118938 S998 D D Y E S N F S V E P P N D P
Sea Urchin Strong. purpuratus Q26614 972 110463 L953 F M G F R A P L S P Q V Y Y K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.2 97.3 86.7 N.A. 89.7 88.7 N.A. N.A. 61.5 63.8 56.4 N.A. 35.5 N.A. 30.9 34.2
Protein Similarity: 100 89.7 98.3 88.5 N.A. 92.5 91.6 N.A. N.A. 72.9 74.6 68.6 N.A. 52.1 N.A. 46.1 49.2
P-Site Identity: 100 100 100 80 N.A. 93.3 93.3 N.A. N.A. 26.6 26.6 13.3 N.A. 13.3 N.A. 26.6 0
P-Site Similarity: 100 100 100 86.6 N.A. 93.3 93.3 N.A. N.A. 26.6 26.6 20 N.A. 33.3 N.A. 40 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 9 0 0 17 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 9 9 9 75 25 0 0 0 0 50 34 0 0 9 17 % D
% Glu: 0 0 0 9 0 0 0 0 0 9 0 9 9 9 17 % E
% Phe: 9 0 0 9 0 0 59 25 0 0 0 0 0 0 0 % F
% Gly: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 34 % G
% His: 0 0 0 0 0 0 0 0 50 17 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % K
% Leu: 0 0 9 0 0 0 0 9 0 0 9 59 17 50 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 9 9 9 0 9 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 9 17 0 0 17 50 17 50 17 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 75 75 50 0 59 25 0 59 9 9 0 0 0 9 9 % S
% Thr: 0 0 0 0 9 0 0 0 17 0 0 0 0 0 9 % T
% Val: 0 0 0 0 0 50 25 0 9 0 0 9 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 0 0 0 0 9 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _