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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KCNA5 All Species: 13.64
Human Site: S116 Identified Species: 30
UniProt: P22460 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22460 NP_002225.2 613 67228 S116 D Q A L G T A S L H H Q R V H
Chimpanzee Pan troglodytes XP_522330 602 66099 S105 D Q A L G T A S L H H Q R V H
Rhesus Macaque Macaca mulatta XP_001102294 605 66481 S105 D Q A L G T A S L H H Q R V H
Dog Lupus familis XP_543859 495 56374 Q51 S G L R F E T Q L K T L A Q F
Cat Felis silvestris
Mouse Mus musculus Q61762 602 66626 S107 Q A P Q D S G S L H H Q R V L
Rat Rattus norvegicus P19024 602 66534 S107 Q A P Q D A G S L H H Q R V L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508339 499 56706 E56 K T L A Q F P E T L L G D P K
Chicken Gallus gallus Q7T199 516 58965 A73 T I F S R F S A E F S E H L V
Frog Xenopus laevis P22739 499 56683 E56 K T L S Q F P E T L L G D P K
Zebra Danio Brachydanio rerio XP_001922996 515 58572 I71 C E R V V I N I S G L R F E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P08510 655 74175 H93 F E P I P H D H D F C E R V V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.2 55.9 N.A. 84.3 86.1 N.A. 58 53.1 56.6 57.7 N.A. 51.7 N.A. N.A. N.A.
Protein Similarity: 100 98 97.5 65 N.A. 87.9 89 N.A. 65.2 63.7 64.4 66.3 N.A. 63.6 N.A. N.A. N.A.
P-Site Identity: 100 100 100 6.6 N.A. 46.6 46.6 N.A. 0 0 0 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 53.3 46.6 N.A. 0 26.6 0 20 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 19 28 10 0 10 28 10 0 0 0 0 10 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 28 0 0 0 19 0 10 0 10 0 0 0 19 0 0 % D
% Glu: 0 19 0 0 0 10 0 19 10 0 0 19 0 10 0 % E
% Phe: 10 0 10 0 10 28 0 0 0 19 0 0 10 0 10 % F
% Gly: 0 10 0 0 28 0 19 0 0 10 0 19 0 0 0 % G
% His: 0 0 0 0 0 10 0 10 0 46 46 0 10 0 28 % H
% Ile: 0 10 0 10 0 10 0 10 0 0 0 0 0 0 0 % I
% Lys: 19 0 0 0 0 0 0 0 0 10 0 0 0 0 19 % K
% Leu: 0 0 28 28 0 0 0 0 55 19 28 10 0 10 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 28 0 10 0 19 0 0 0 0 0 0 19 0 % P
% Gln: 19 28 0 19 19 0 0 10 0 0 0 46 0 10 0 % Q
% Arg: 0 0 10 10 10 0 0 0 0 0 0 10 55 0 0 % R
% Ser: 10 0 0 19 0 10 10 46 10 0 10 0 0 0 0 % S
% Thr: 10 19 0 0 0 28 10 0 19 0 10 0 0 0 10 % T
% Val: 0 0 0 10 10 0 0 0 0 0 0 0 0 55 19 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _