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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SPRR2E All Species: 7.27
Human Site: S60 Identified Species: 32
UniProt: P22531 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22531 NP_001019380.2 72 7855 S60 K C P P V T P S P P C Q P K C
Chimpanzee Pan troglodytes XP_001136449 97 10747 S83 K V P E P C P S T V T P A P A
Rhesus Macaque Macaca mulatta P35322 89 9833 T78 E P C P S T V T P A P A Q Q K
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus O70561 109 11800 S96 N Q K K R T E S I L H K P I A
Rat Rattus norvegicus Q63532 152 16715 E134 P C Q P V V P E P C P P T V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518081 265 30543 S253 K C T P V Q P S P C C Q G K F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 45.3 47.1 N.A. N.A. 25.6 38.1 N.A. 22.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 50.5 53.9 N.A. N.A. 33 41.4 N.A. 25.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 26.6 20 N.A. N.A. 20 33.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 26.6 40 N.A. N.A. 26.6 33.3 N.A. 66.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 17 0 17 17 0 34 % A
% Cys: 0 50 17 0 0 17 0 0 0 34 34 0 0 0 17 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 17 0 0 17 0 0 17 17 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 17 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 17 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 17 0 0 0 0 17 0 % I
% Lys: 50 0 17 17 0 0 0 0 0 0 0 17 0 34 17 % K
% Leu: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 17 17 34 67 17 0 67 0 67 17 34 34 34 17 0 % P
% Gln: 0 17 17 0 0 17 0 0 0 0 0 34 17 17 0 % Q
% Arg: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 17 0 0 67 0 0 0 0 0 0 0 % S
% Thr: 0 0 17 0 0 50 0 17 17 0 17 0 17 0 17 % T
% Val: 0 17 0 0 50 17 17 0 0 17 0 0 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _