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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALAS2
All Species:
31.21
Human Site:
S233
Identified Species:
62.42
UniProt:
P22557
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22557
NP_000023.2
587
64633
S233
T
R
N
I
S
G
T
S
K
F
H
V
E
L
E
Chimpanzee
Pan troglodytes
XP_528998
559
61798
E230
A
R
S
N
L
K
V
E
V
G
V
L
G
Q
K
Rhesus Macaque
Macaca mulatta
XP_001093098
580
63864
F228
N
I
S
G
T
S
K
F
H
V
E
L
E
Q
E
Dog
Lupus familis
XP_548619
587
65062
S233
T
R
N
I
S
G
T
S
K
F
H
V
E
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P08680
587
64735
S233
T
R
N
I
S
G
T
S
K
F
H
V
E
L
E
Rat
Rattus norvegicus
Q63147
587
64823
S233
T
R
N
I
S
G
T
S
K
F
H
V
E
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510619
581
64480
S227
T
R
N
I
S
G
T
S
K
F
H
V
D
L
E
Chicken
Gallus gallus
P07997
635
69930
S282
T
R
N
I
S
G
T
S
K
F
H
V
D
L
E
Frog
Xenopus laevis
NP_001087499
609
66693
S255
T
R
N
I
S
G
T
S
K
Y
H
V
D
L
E
Zebra Danio
Brachydanio rerio
Q9YHT4
583
63890
S228
T
R
N
I
S
G
T
S
N
Y
H
V
A
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09950
548
59344
N229
K
K
H
I
F
K
H
N
D
L
N
E
L
E
Q
Red Bread Mold
Neurospora crassa
Q7RVY5
629
67428
N229
K
H
A
V
E
L
E
N
S
L
A
K
L
H
A
Conservation
Percent
Protein Identity:
100
84.6
80.4
91.8
N.A.
90.1
88.7
N.A.
74.2
57.9
67.6
66
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.1
85.1
95
N.A.
93.8
92.8
N.A.
83.4
71.8
79.1
77.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
13.3
100
N.A.
100
100
N.A.
93.3
93.3
86.6
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.8
39.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.7
55.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
0
0
9
0
9
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
9
0
0
0
25
0
0
% D
% Glu:
0
0
0
0
9
0
9
9
0
0
9
9
42
9
75
% E
% Phe:
0
0
0
0
9
0
0
9
0
50
0
0
0
0
0
% F
% Gly:
0
0
0
9
0
67
0
0
0
9
0
0
9
0
0
% G
% His:
0
9
9
0
0
0
9
0
9
0
67
0
0
9
0
% H
% Ile:
0
9
0
75
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
9
0
0
0
17
9
0
59
0
0
9
0
0
9
% K
% Leu:
0
0
0
0
9
9
0
0
0
17
0
17
17
67
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
67
9
0
0
0
17
9
0
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
9
% Q
% Arg:
0
75
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
17
0
67
9
0
67
9
0
0
0
0
0
0
% S
% Thr:
67
0
0
0
9
0
67
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
9
0
9
9
9
67
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _