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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ALAS2
All Species:
36.06
Human Site:
Y279
Identified Species:
72.12
UniProt:
P22557
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22557
NP_000023.2
587
64633
Y279
I
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Chimpanzee
Pan troglodytes
XP_528998
559
61798
V273
N
S
G
A
A
K
F
V
F
R
H
N
D
P
D
Rhesus Macaque
Macaca mulatta
XP_001093098
580
63864
Y272
I
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Dog
Lupus familis
XP_548619
587
65062
Y279
I
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Cat
Felis silvestris
Mouse
Mus musculus
P08680
587
64735
Y279
L
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Rat
Rattus norvegicus
Q63147
587
64823
Y279
L
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510619
581
64480
Y273
M
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Chicken
Gallus gallus
P07997
635
69930
Y328
M
L
P
G
C
E
I
Y
S
D
S
G
N
H
A
Frog
Xenopus laevis
NP_001087499
609
66693
Y301
M
L
P
G
C
E
I
Y
S
D
A
G
N
H
A
Zebra Danio
Brachydanio rerio
Q9YHT4
583
63890
Y274
M
L
P
G
C
E
I
Y
S
D
M
G
N
H
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P09950
548
59344
K273
K
I
C
D
L
A
D
K
Y
G
A
L
T
F
L
Red Bread Mold
Neurospora crassa
Q7RVY5
629
67428
N272
V
I
L
S
D
S
L
N
H
A
S
M
I
Q
G
Conservation
Percent
Protein Identity:
100
84.6
80.4
91.8
N.A.
90.1
88.7
N.A.
74.2
57.9
67.6
66
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
86.1
85.1
95
N.A.
93.8
92.8
N.A.
83.4
71.8
79.1
77.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
93.3
93.3
N.A.
93.3
86.6
93.3
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
100
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
37.8
39.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
57.7
55.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
0
0
0
9
67
0
0
0
75
% A
% Cys:
0
0
9
0
75
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
9
0
9
0
0
75
0
0
9
0
9
% D
% Glu:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
9
0
0
0
0
9
0
% F
% Gly:
0
0
9
75
0
0
0
0
0
9
0
75
0
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
9
0
0
75
0
% H
% Ile:
25
17
0
0
0
0
75
0
0
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% K
% Leu:
17
75
9
0
9
0
9
0
0
0
0
9
0
0
9
% L
% Met:
34
0
0
0
0
0
0
0
0
0
9
9
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
9
0
0
0
9
75
0
0
% N
% Pro:
0
0
75
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
9
0
9
0
9
0
0
75
0
17
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
9
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
75
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _