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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDXR
All Species:
16.36
Human Site:
S298
Identified Species:
27.69
UniProt:
P22570
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22570
NP_004101.2
491
53837
S298
A
E
A
A
R
Q
A
S
A
S
R
A
W
G
L
Chimpanzee
Pan troglodytes
XP_001137746
494
53873
S301
E
E
A
A
R
Q
A
S
A
S
R
A
W
G
L
Rhesus Macaque
Macaca mulatta
XP_001091261
492
53992
S299
E
E
A
A
R
W
A
S
A
S
R
A
W
G
L
Dog
Lupus familis
XP_533117
492
54038
S299
E
E
A
A
R
Q
A
S
A
S
R
T
W
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61578
494
54184
L301
E
E
A
A
R
Q
A
L
A
S
R
A
W
G
L
Rat
Rattus norvegicus
P56522
494
54344
L301
E
E
A
A
R
R
A
L
A
S
R
A
W
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513817
497
53440
T304
E
A
V
A
R
P
S
T
A
P
R
A
W
G
F
Chicken
Gallus gallus
XP_001232923
471
51228
A277
K
A
V
M
A
Q
A
A
V
P
R
Q
W
G
L
Frog
Xenopus laevis
NP_001088306
486
53595
R292
K
V
E
A
N
W
A
R
A
E
K
E
W
G
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3T9
466
51334
M272
R
K
R
L
T
E
L
M
L
K
S
L
K
E
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790150
503
55169
G300
A
R
Q
D
A
A
S
G
E
W
H
L
D
F
F
Poplar Tree
Populus trichocarpa
XP_002301734
496
54084
S291
A
P
S
H
P
S
S
S
Q
R
E
L
H
F
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194962
483
53051
D282
K
T
S
E
A
D
P
D
Q
R
E
L
H
F
V
Baker's Yeast
Sacchar. cerevisiae
P48360
493
56219
P296
K
K
N
Y
K
K
A
P
P
P
S
S
G
Y
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
97.7
89.8
N.A.
86.6
86.8
N.A.
76
65.9
66.1
N.A.
N.A.
46.6
N.A.
N.A.
52.8
Protein Similarity:
100
92.9
98.3
93.9
N.A.
91.3
92.1
N.A.
83.3
78.4
76.3
N.A.
N.A.
62.5
N.A.
N.A.
67.7
P-Site Identity:
100
93.3
86.6
86.6
N.A.
86.6
80
N.A.
46.6
40
40
N.A.
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
93.3
86.6
86.6
N.A.
86.6
86.6
N.A.
60
46.6
46.6
N.A.
N.A.
13.3
N.A.
N.A.
13.3
Percent
Protein Identity:
47.5
N.A.
N.A.
46.4
35.2
N.A.
Protein Similarity:
61
N.A.
N.A.
60.9
54.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
43
58
22
8
65
8
58
0
0
43
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
8
0
8
0
0
0
0
8
0
8
% D
% Glu:
43
43
8
8
0
8
0
0
8
8
15
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
22
15
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
8
65
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
8
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
29
15
0
0
8
8
0
0
0
8
8
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
8
15
8
0
0
29
0
0
58
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
8
0
0
8
8
8
8
8
22
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
36
0
0
15
0
0
8
0
0
8
% Q
% Arg:
8
8
8
0
50
8
0
8
0
15
58
0
0
0
0
% R
% Ser:
0
0
15
0
0
8
22
36
0
43
15
8
0
0
0
% S
% Thr:
0
8
0
0
8
0
0
8
0
0
0
8
0
0
0
% T
% Val:
0
8
15
0
0
0
0
0
8
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
15
0
0
0
8
0
0
65
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _