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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FDXR All Species: 40.61
Human Site: S364 Identified Species: 68.72
UniProt: P22570 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22570 NP_004101.2 491 53837 S364 L S S I G Y K S R P V D P S V
Chimpanzee Pan troglodytes XP_001137746 494 53873 S367 L S S I G Y K S R P V D P S V
Rhesus Macaque Macaca mulatta XP_001091261 492 53992 S365 L S S V G Y K S R P V D P S V
Dog Lupus familis XP_533117 492 54038 S365 L S S V G Y K S R P I D P S V
Cat Felis silvestris
Mouse Mus musculus Q61578 494 54184 S367 L S S V G Y K S R P I D P S V
Rat Rattus norvegicus P56522 494 54344 S367 L S S V G Y K S R P I D P S V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513817 497 53440 S370 L S S V G Y K S R P I D P S V
Chicken Gallus gallus XP_001232923 471 51228 S343 L S S I G Y R S L P L D P A V
Frog Xenopus laevis NP_001088306 486 53595 S358 F S S I G Y K S A S I S S T V
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3T9 466 51334 S338 L R S I G Y K S S C V D T G I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790150 503 55169 S366 L R S I G Y K S V Q V D D F I
Poplar Tree Populus trichocarpa XP_002301734 496 54084 K357 V L K S I G Y K S V P V D G L
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194962 483 53051 K348 V L K A I G Y K S V P V N G L
Baker's Yeast Sacchar. cerevisiae P48360 493 56219 L362 V D L L I T S L G Y A G V P M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 97.7 89.8 N.A. 86.6 86.8 N.A. 76 65.9 66.1 N.A. N.A. 46.6 N.A. N.A. 52.8
Protein Similarity: 100 92.9 98.3 93.9 N.A. 91.3 92.1 N.A. 83.3 78.4 76.3 N.A. N.A. 62.5 N.A. N.A. 67.7
P-Site Identity: 100 100 93.3 86.6 N.A. 86.6 86.6 N.A. 86.6 73.3 53.3 N.A. N.A. 60 N.A. N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 66.6 N.A. N.A. 66.6 N.A. N.A. 66.6
Percent
Protein Identity: 47.5 N.A. N.A. 46.4 35.2 N.A.
Protein Similarity: 61 N.A. N.A. 60.9 54.9 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 8 0 8 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 72 15 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % F
% Gly: 0 0 0 0 79 15 0 0 8 0 0 8 0 22 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 43 22 0 0 0 0 0 36 0 0 0 15 % I
% Lys: 0 0 15 0 0 0 72 15 0 0 0 0 0 0 0 % K
% Leu: 72 15 8 8 0 0 0 8 8 0 8 0 0 0 15 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 58 15 0 58 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % Q
% Arg: 0 15 0 0 0 0 8 0 50 0 0 0 0 0 0 % R
% Ser: 0 65 79 8 0 0 8 79 22 8 0 8 8 50 0 % S
% Thr: 0 0 0 0 0 8 0 0 0 0 0 0 8 8 0 % T
% Val: 22 0 0 36 0 0 0 0 8 15 36 15 8 0 65 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 79 15 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _