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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDXR
All Species:
22.12
Human Site:
S375
Identified Species:
37.44
UniProt:
P22570
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22570
NP_004101.2
491
53837
S375
D
P
S
V
P
F
D
S
K
L
G
V
I
P
N
Chimpanzee
Pan troglodytes
XP_001137746
494
53873
S378
D
P
S
V
P
F
D
S
K
L
G
V
I
P
N
Rhesus Macaque
Macaca mulatta
XP_001091261
492
53992
S376
D
P
S
V
P
F
D
S
K
L
G
V
I
P
N
Dog
Lupus familis
XP_533117
492
54038
S376
D
P
S
V
P
F
D
S
K
R
G
V
I
P
N
Cat
Felis silvestris
Mouse
Mus musculus
Q61578
494
54184
P378
D
P
S
V
P
F
D
P
K
L
G
V
I
P
N
Rat
Rattus norvegicus
P56522
494
54344
P378
D
P
S
V
P
F
D
P
K
L
G
I
I
P
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513817
497
53440
P381
D
P
S
V
P
F
D
P
E
R
G
V
I
P
N
Chicken
Gallus gallus
XP_001232923
471
51228
T354
D
P
A
V
P
F
D
T
Q
H
S
I
I
P
N
Frog
Xenopus laevis
NP_001088306
486
53595
P369
S
S
T
V
P
F
L
P
K
Q
G
V
I
P
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3T9
466
51334
T349
D
T
G
I
N
F
D
T
R
R
G
R
V
H
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790150
503
55169
H377
D
D
F
I
P
F
D
H
Q
K
G
V
V
K
N
Poplar Tree
Populus trichocarpa
XP_002301734
496
54084
H368
V
D
G
L
P
F
D
H
E
K
G
V
V
P
N
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194962
483
53051
H359
V
N
G
L
P
F
D
H
K
K
G
V
V
P
N
Baker's Yeast
Sacchar. cerevisiae
P48360
493
56219
S373
G
V
P
M
P
E
F
S
K
L
S
I
G
F
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
97.7
89.8
N.A.
86.6
86.8
N.A.
76
65.9
66.1
N.A.
N.A.
46.6
N.A.
N.A.
52.8
Protein Similarity:
100
92.9
98.3
93.9
N.A.
91.3
92.1
N.A.
83.3
78.4
76.3
N.A.
N.A.
62.5
N.A.
N.A.
67.7
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
80
60
60
N.A.
N.A.
33.3
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
86.6
86.6
66.6
N.A.
N.A.
60
N.A.
N.A.
66.6
Percent
Protein Identity:
47.5
N.A.
N.A.
46.4
35.2
N.A.
Protein Similarity:
61
N.A.
N.A.
60.9
54.9
N.A.
P-Site Identity:
46.6
N.A.
N.A.
53.3
26.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
66.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
15
0
0
0
0
86
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
0
8
0
0
15
0
0
0
0
0
0
% E
% Phe:
0
0
8
0
0
93
8
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
22
0
0
0
0
0
0
0
86
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
22
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
15
0
0
0
0
0
0
0
22
65
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
65
22
0
0
0
8
0
% K
% Leu:
0
0
0
15
0
0
8
0
0
43
0
0
0
0
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
93
% N
% Pro:
0
58
8
0
93
0
0
29
0
0
0
0
0
79
0
% P
% Gln:
0
0
0
0
0
0
0
0
15
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
22
0
8
0
0
0
% R
% Ser:
8
8
50
0
0
0
0
36
0
0
15
0
0
0
0
% S
% Thr:
0
8
8
0
0
0
0
15
0
0
0
0
0
0
0
% T
% Val:
15
8
0
65
0
0
0
0
0
0
0
72
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _