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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDXR
All Species:
41.82
Human Site:
S396
Identified Species:
70.77
UniProt:
P22570
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22570
NP_004101.2
491
53837
S396
D
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Chimpanzee
Pan troglodytes
XP_001137746
494
53873
S399
D
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Rhesus Macaque
Macaca mulatta
XP_001091261
492
53992
S397
D
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Dog
Lupus familis
XP_533117
492
54038
S397
D
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61578
494
54184
S399
N
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Rat
Rattus norvegicus
P56522
494
54344
S399
N
A
P
G
L
Y
C
S
G
W
V
K
R
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513817
497
53440
S402
R
A
P
G
L
Y
C
S
G
W
V
K
R
G
P
Chicken
Gallus gallus
XP_001232923
471
51228
S375
G
V
P
G
L
Y
C
S
G
W
V
K
R
G
P
Frog
Xenopus laevis
NP_001088306
486
53595
S390
G
I
P
G
L
Y
C
S
G
W
V
K
R
G
P
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3T9
466
51334
A377
V
D
P
G
L
Y
V
A
G
W
L
G
T
G
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790150
503
55169
S398
G
I
Q
G
L
Y
C
S
G
W
V
K
R
G
P
Poplar Tree
Populus trichocarpa
XP_002301734
496
54084
C398
L
E
K
G
L
Y
V
C
G
W
L
K
R
G
P
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194962
483
53051
C389
T
E
P
G
L
Y
V
C
G
W
L
K
R
G
P
Baker's Yeast
Sacchar. cerevisiae
P48360
493
56219
S405
I
F
P
H
L
Y
A
S
G
W
I
R
K
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
97.7
89.8
N.A.
86.6
86.8
N.A.
76
65.9
66.1
N.A.
N.A.
46.6
N.A.
N.A.
52.8
Protein Similarity:
100
92.9
98.3
93.9
N.A.
91.3
92.1
N.A.
83.3
78.4
76.3
N.A.
N.A.
62.5
N.A.
N.A.
67.7
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
86.6
93.3
86.6
N.A.
N.A.
53.3
N.A.
N.A.
80
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
86.6
93.3
93.3
N.A.
N.A.
66.6
N.A.
N.A.
86.6
Percent
Protein Identity:
47.5
N.A.
N.A.
46.4
35.2
N.A.
Protein Similarity:
61
N.A.
N.A.
60.9
54.9
N.A.
P-Site Identity:
60
N.A.
N.A.
66.6
46.6
N.A.
P-Site Similarity:
66.6
N.A.
N.A.
73.3
66.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
0
0
0
8
8
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
72
15
0
0
0
0
0
0
0
% C
% Asp:
29
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
22
0
0
93
0
0
0
0
100
0
0
8
0
100
0
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
15
0
0
0
0
0
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
86
8
0
0
% K
% Leu:
8
0
0
0
100
0
0
0
0
0
22
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
86
0
0
0
0
0
0
0
0
0
0
0
93
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
86
0
0
% R
% Ser:
0
0
0
0
0
0
0
79
0
0
0
0
0
0
8
% S
% Thr:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
8
43
0
0
0
0
22
0
0
0
72
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _