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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FDXR
All Species:
30.3
Human Site:
S454
Identified Species:
51.28
UniProt:
P22570
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22570
NP_004101.2
491
53837
S454
S
R
G
V
R
P
V
S
F
S
D
W
E
K
L
Chimpanzee
Pan troglodytes
XP_001137746
494
53873
S457
S
R
G
V
R
P
V
S
F
S
E
W
E
K
L
Rhesus Macaque
Macaca mulatta
XP_001091261
492
53992
S455
S
R
G
V
R
P
V
S
F
S
N
W
E
K
L
Dog
Lupus familis
XP_533117
492
54038
S455
S
R
G
V
R
P
V
S
F
S
D
W
E
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61578
494
54184
S457
N
R
G
V
R
P
V
S
F
S
D
W
E
K
L
Rat
Rattus norvegicus
P56522
494
54344
S457
D
R
G
V
R
P
V
S
F
S
D
W
E
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513817
497
53440
T460
S
R
G
V
Q
A
L
T
F
S
D
W
E
R
L
Chicken
Gallus gallus
XP_001232923
471
51228
V433
R
S
R
G
I
R
P
V
S
F
S
E
W
E
K
Frog
Xenopus laevis
NP_001088306
486
53595
V448
H
L
R
G
I
Q
P
V
S
F
S
D
W
E
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3T9
466
51334
R435
V
T
W
D
G
W
Q
R
I
N
D
F
E
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790150
503
55169
T456
E
R
G
V
T
P
I
T
F
S
D
W
T
K
I
Poplar Tree
Populus trichocarpa
XP_002301734
496
54084
R456
L
L
D
N
R
G
V
R
V
V
P
F
S
A
W
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_194962
483
53051
F447
R
K
V
K
K
V
E
F
S
G
W
E
K
I
D
Baker's Yeast
Sacchar. cerevisiae
P48360
493
56219
N463
W
K
D
W
E
R
I
N
K
K
E
L
L
R
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.3
97.7
89.8
N.A.
86.6
86.8
N.A.
76
65.9
66.1
N.A.
N.A.
46.6
N.A.
N.A.
52.8
Protein Similarity:
100
92.9
98.3
93.9
N.A.
91.3
92.1
N.A.
83.3
78.4
76.3
N.A.
N.A.
62.5
N.A.
N.A.
67.7
P-Site Identity:
100
93.3
93.3
100
N.A.
93.3
93.3
N.A.
66.6
0
0
N.A.
N.A.
13.3
N.A.
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
6.6
6.6
N.A.
N.A.
26.6
N.A.
N.A.
80
Percent
Protein Identity:
47.5
N.A.
N.A.
46.4
35.2
N.A.
Protein Similarity:
61
N.A.
N.A.
60.9
54.9
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
20
N.A.
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
15
8
0
0
0
0
0
0
50
8
0
0
8
% D
% Glu:
8
0
0
0
8
0
8
0
0
0
15
15
58
15
0
% E
% Phe:
0
0
0
0
0
0
0
8
58
15
0
15
0
0
0
% F
% Gly:
0
0
58
15
8
8
0
0
0
8
0
0
0
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
15
0
15
0
8
0
0
0
0
8
8
% I
% Lys:
0
15
0
8
8
0
0
0
8
8
0
0
8
50
15
% K
% Leu:
8
15
0
0
0
0
8
0
0
0
0
8
8
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
50
15
0
0
0
8
0
0
0
0
% P
% Gln:
0
0
0
0
8
8
8
0
0
0
0
0
0
0
0
% Q
% Arg:
15
58
15
0
50
15
0
15
0
0
0
0
0
15
0
% R
% Ser:
36
8
0
0
0
0
0
43
22
58
15
0
8
8
0
% S
% Thr:
0
8
0
0
8
0
0
15
0
0
0
0
8
0
0
% T
% Val:
8
0
8
58
0
8
50
15
8
8
0
0
0
0
0
% V
% Trp:
8
0
8
8
0
8
0
0
0
0
8
58
15
0
8
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _