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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FDXR All Species: 41.82
Human Site: Y362 Identified Species: 70.77
UniProt: P22570 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22570 NP_004101.2 491 53837 Y362 L V L S S I G Y K S R P V D P
Chimpanzee Pan troglodytes XP_001137746 494 53873 Y365 L V L S S I G Y K S R P V D P
Rhesus Macaque Macaca mulatta XP_001091261 492 53992 Y363 L V L S S V G Y K S R P V D P
Dog Lupus familis XP_533117 492 54038 Y363 L V L S S V G Y K S R P I D P
Cat Felis silvestris
Mouse Mus musculus Q61578 494 54184 Y365 L L L S S V G Y K S R P I D P
Rat Rattus norvegicus P56522 494 54344 Y365 L L L S S V G Y K S R P I D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513817 497 53440 Y368 L V L S S V G Y K S R P I D P
Chicken Gallus gallus XP_001232923 471 51228 Y341 L V L S S I G Y R S L P L D P
Frog Xenopus laevis NP_001088306 486 53595 Y356 L I F S S I G Y K S A S I S S
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3T9 466 51334 Y336 L I L R S I G Y K S S C V D T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790150 503 55169 Y364 L V L R S I G Y K S V Q V D D
Poplar Tree Populus trichocarpa XP_002301734 496 54084 G355 G L V L K S I G Y K S V P V D
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194962 483 53051 G346 S M V L K A I G Y K S V P V N
Baker's Yeast Sacchar. cerevisiae P48360 493 56219 T360 Y K V D L L I T S L G Y A G V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 91.3 97.7 89.8 N.A. 86.6 86.8 N.A. 76 65.9 66.1 N.A. N.A. 46.6 N.A. N.A. 52.8
Protein Similarity: 100 92.9 98.3 93.9 N.A. 91.3 92.1 N.A. 83.3 78.4 76.3 N.A. N.A. 62.5 N.A. N.A. 67.7
P-Site Identity: 100 100 93.3 86.6 N.A. 80 80 N.A. 86.6 80 53.3 N.A. N.A. 66.6 N.A. N.A. 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 93.3 66.6 N.A. N.A. 73.3 N.A. N.A. 73.3
Percent
Protein Identity: 47.5 N.A. N.A. 46.4 35.2 N.A.
Protein Similarity: 61 N.A. N.A. 60.9 54.9 N.A.
P-Site Identity: 0 N.A. N.A. 0 0 N.A.
P-Site Similarity: 13.3 N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 8 0 0 0 0 8 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 0 0 0 8 0 0 0 0 0 0 0 0 0 72 15 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 0 79 15 0 0 8 0 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 15 0 0 0 43 22 0 0 0 0 0 36 0 0 % I
% Lys: 0 8 0 0 15 0 0 0 72 15 0 0 0 0 0 % K
% Leu: 79 22 72 15 8 8 0 0 0 8 8 0 8 0 0 % L
% Met: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 58 15 0 58 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 0 0 0 15 0 0 0 0 8 0 50 0 0 0 0 % R
% Ser: 8 0 0 65 79 8 0 0 8 79 22 8 0 8 8 % S
% Thr: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % T
% Val: 0 50 22 0 0 36 0 0 0 0 8 15 36 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 79 15 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _