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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
17.27
Human Site:
S468
Identified Species:
34.55
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
S468
A
D
P
K
W
E
L
S
R
A
R
L
T
L
G
Chimpanzee
Pan troglodytes
XP_521622
819
91776
P475
E
D
P
K
W
E
F
P
R
D
K
L
T
L
G
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
S468
A
D
P
K
W
E
L
S
R
A
R
L
T
L
G
Dog
Lupus familis
XP_545926
833
90729
S495
A
D
P
K
W
E
L
S
R
A
R
L
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
S462
A
D
P
K
W
E
L
S
R
T
R
L
T
L
G
Rat
Rattus norvegicus
Q04589
822
91806
P474
E
D
P
R
W
E
L
P
R
D
R
L
V
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
A462
P
D
P
K
W
E
L
A
R
S
R
L
T
L
G
Frog
Xenopus laevis
O42127
802
89497
L458
L
D
P
K
W
E
L
L
R
S
R
L
T
L
G
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
T456
S
D
P
K
W
E
F
T
R
T
K
L
T
L
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
A426
G
A
T
L
G
E
G
A
F
G
R
V
V
M
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
E636
S
D
P
V
W
E
V
E
R
S
K
L
S
L
V
Sea Urchin
Strong. purpuratus
Q26614
972
110463
P635
L
D
P
E
W
E
F
P
R
D
R
L
T
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
66.6
100
100
N.A.
93.3
66.6
N.A.
N.A.
80
80
66.6
N.A.
13.3
N.A.
46.6
60
P-Site Similarity:
100
73.3
100
100
N.A.
93.3
73.3
N.A.
N.A.
93.3
86.6
86.6
N.A.
33.3
N.A.
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
9
0
0
0
0
0
17
0
25
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
92
0
0
0
0
0
0
0
25
0
0
0
0
0
% D
% Glu:
17
0
0
9
0
100
0
9
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
25
0
9
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
9
0
0
9
0
0
0
0
84
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
67
0
0
0
0
0
0
25
0
0
0
0
% K
% Leu:
17
0
0
9
0
0
59
9
0
0
0
92
0
84
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
92
0
0
0
0
25
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
92
0
75
0
0
0
0
% R
% Ser:
17
0
0
0
0
0
0
34
0
25
0
0
9
0
0
% S
% Thr:
0
0
9
0
0
0
0
9
0
17
0
0
75
0
0
% T
% Val:
0
0
0
9
0
0
9
0
0
0
0
9
17
9
9
% V
% Trp:
0
0
0
0
92
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _