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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
30.61
Human Site:
S578
Identified Species:
61.21
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
S578
R
P
P
G
L
D
Y
S
F
D
T
C
K
P
P
Chimpanzee
Pan troglodytes
XP_521622
819
91776
S585
R
P
P
G
M
E
Y
S
Y
D
I
N
R
V
P
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
S578
R
P
P
G
L
D
Y
S
F
D
T
C
K
P
P
Dog
Lupus familis
XP_545926
833
90729
S605
R
P
P
G
M
D
Y
S
F
D
T
C
K
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
S572
R
P
P
G
M
D
Y
S
F
D
A
C
R
L
P
Rat
Rattus norvegicus
Q04589
822
91806
C584
R
P
P
G
L
E
Y
C
Y
N
P
S
H
N
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
S572
R
P
P
G
M
D
Y
S
F
D
T
C
K
L
P
Frog
Xenopus laevis
O42127
802
89497
S568
R
P
P
G
M
D
Y
S
F
D
A
C
K
I
P
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
S566
R
P
P
G
M
D
Y
S
F
D
T
C
K
I
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
S517
R
D
Q
D
R
D
S
S
Q
P
P
P
S
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
S758
Y
L
E
P
R
K
A
S
D
K
D
D
I
E
L
Sea Urchin
Strong. purpuratus
Q26614
972
110463
E742
R
R
P
P
E
E
Y
E
K
S
I
L
L
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
53.3
100
86.6
N.A.
73.3
46.6
N.A.
N.A.
86.6
80
86.6
N.A.
33.3
N.A.
6.6
20
P-Site Similarity:
100
80
100
93.3
N.A.
86.6
66.6
N.A.
N.A.
93.3
86.6
93.3
N.A.
33.3
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
59
0
0
0
% C
% Asp:
0
9
0
9
0
67
0
0
9
67
9
9
0
0
0
% D
% Glu:
0
0
9
0
9
25
0
9
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% F
% Gly:
0
0
0
75
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
17
0
9
17
0
% I
% Lys:
0
0
0
0
0
9
0
0
9
9
0
0
50
0
0
% K
% Leu:
0
9
0
0
25
0
0
0
0
0
0
9
9
25
9
% L
% Met:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
9
0
9
0
% N
% Pro:
0
75
84
17
0
0
0
0
0
9
17
9
0
25
84
% P
% Gln:
0
0
9
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
92
9
0
0
17
0
0
0
0
0
0
0
17
0
0
% R
% Ser:
0
0
0
0
0
0
9
84
0
9
0
9
9
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
42
0
0
9
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
84
0
17
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _