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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FGFR3
All Species:
9.35
Human Site:
S800
Identified Species:
18.7
UniProt:
P22607
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22607
NP_000133.1
806
87710
S800
L
L
P
P
A
P
P
S
S
G
G
S
R
T
_
Chimpanzee
Pan troglodytes
XP_521622
819
91776
L807
P
M
P
Y
E
P
C
L
P
Q
Y
P
H
I
N
Rhesus Macaque
Macaca mulatta
XP_001101108
806
87642
S800
L
L
P
P
A
P
P
S
S
G
G
S
R
T
_
Dog
Lupus familis
XP_545926
833
90729
G827
L
L
P
P
A
P
P
G
G
G
G
P
R
T
_
Cat
Felis silvestris
Mouse
Mus musculus
Q61851
801
87739
S795
L
L
P
P
G
P
P
S
N
G
G
P
R
T
_
Rat
Rattus norvegicus
Q04589
822
91806
C806
E
P
F
P
E
E
P
C
L
P
R
H
P
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P18460
806
89712
L794
L
L
P
D
E
P
C
L
P
K
H
V
P
C
N
Frog
Xenopus laevis
O42127
802
89497
L790
I
L
P
D
E
P
C
L
P
K
H
Q
Q
H
N
Zebra Danio
Brachydanio rerio
Q9I8X3
800
89698
L788
P
L
P
E
E
P
C
L
P
K
H
H
H
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07407
729
82568
D721
D
E
E
E
D
E
T
D
N
L
Q
K
W
C
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10656
1040
118938
N980
R
P
L
S
A
P
V
N
L
P
S
E
P
Q
H
Sea Urchin
Strong. purpuratus
Q26614
972
110463
T964
V
Y
Y
K
V
P
Q
T
R
D
C
C
P
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.2
99.1
89.3
N.A.
92.4
62.9
N.A.
N.A.
80.1
70.5
73.8
N.A.
37.5
N.A.
31.3
35.4
Protein Similarity:
100
77.5
99.2
91.9
N.A.
94.7
76.2
N.A.
N.A.
87.5
79.4
82.3
N.A.
54
N.A.
46.6
50
P-Site Identity:
100
13.3
100
78.5
N.A.
78.5
20
N.A.
N.A.
26.6
20
20
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
20
100
78.5
N.A.
85.7
20
N.A.
N.A.
26.6
33.3
26.6
N.A.
6.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
34
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
34
9
0
0
9
9
0
17
0
% C
% Asp:
9
0
0
17
9
0
0
9
0
9
0
0
0
0
0
% D
% Glu:
9
9
9
17
42
17
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
9
0
0
9
9
34
34
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
25
17
17
9
9
% H
% Ile:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
9
0
0
0
0
0
25
0
9
0
0
0
% K
% Leu:
42
59
9
0
0
0
0
34
17
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
17
0
0
0
0
0
42
% N
% Pro:
17
17
67
42
0
84
42
0
34
17
0
25
34
0
0
% P
% Gln:
0
0
0
0
0
0
9
0
0
9
9
9
9
9
9
% Q
% Arg:
9
0
0
0
0
0
0
0
9
0
9
0
34
0
0
% R
% Ser:
0
0
0
9
0
0
0
25
17
0
9
17
0
9
0
% S
% Thr:
0
0
0
0
0
0
9
9
0
0
0
0
0
42
0
% T
% Val:
9
0
0
0
9
0
9
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
0
9
9
9
0
0
0
0
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
34
% _