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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HNRNPA2B1
All Species:
21.52
Human Site:
S259
Identified Species:
43.03
UniProt:
P22626
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22626
NP_002128.1
353
37430
S259
G
G
G
N
F
G
G
S
P
G
Y
G
G
G
R
Chimpanzee
Pan troglodytes
XP_519003
614
65114
S520
G
G
G
N
F
G
G
S
P
G
Y
G
G
G
R
Rhesus Macaque
Macaca mulatta
XP_001086138
320
34397
G227
R
N
F
S
G
R
G
G
F
G
G
S
H
G
G
Dog
Lupus familis
XP_864315
328
34822
P235
S
G
N
F
G
G
S
P
G
Y
G
G
G
R
G
Cat
Felis silvestris
Mouse
Mus musculus
O88569
353
37384
S259
G
G
G
N
F
G
G
S
P
G
Y
G
G
G
R
Rat
Rattus norvegicus
A7VJC2
353
37459
S259
G
G
G
N
F
G
G
S
P
G
Y
G
G
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510026
344
36175
Y250
N
F
G
G
S
P
G
Y
G
G
G
R
G
G
Y
Chicken
Gallus gallus
Q5ZI72
301
33425
S208
Q
Q
Q
K
G
G
K
S
N
A
S
G
G
R
G
Frog
Xenopus laevis
P51989
346
36541
G252
G
G
G
P
S
Y
G
G
G
R
G
G
G
Y
G
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P48810
385
39481
S262
G
G
G
Q
G
G
G
S
G
G
W
N
Q
Q
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22037
346
36325
Y252
G
G
G
G
Q
G
G
Y
G
G
D
Y
G
G
G
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
Y395
Q
K
Q
T
G
M
D
Y
T
Q
M
Y
Q
Q
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
57.2
92.3
N.A.
99.7
99.7
N.A.
96.3
33.4
86.9
N.A.
N.A.
44.9
N.A.
45.3
N.A.
Protein Similarity:
100
57.4
69.1
92.6
N.A.
100
99.7
N.A.
96.5
51.2
90.9
N.A.
N.A.
60
N.A.
58.6
N.A.
P-Site Identity:
100
100
20
26.6
N.A.
100
100
N.A.
33.3
26.6
40
N.A.
N.A.
46.6
N.A.
53.3
N.A.
P-Site Similarity:
100
100
26.6
26.6
N.A.
100
100
N.A.
33.3
26.6
40
N.A.
N.A.
53.3
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
32.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
9
9
9
34
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
59
67
67
17
42
67
75
17
42
67
34
59
75
59
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
9
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% M
% Asn:
9
9
9
34
0
0
0
0
9
0
0
9
0
0
0
% N
% Pro:
0
0
0
9
0
9
0
9
34
0
0
0
0
0
0
% P
% Gln:
17
9
17
9
9
0
0
0
0
9
0
0
17
17
9
% Q
% Arg:
9
0
0
0
0
9
0
0
0
9
0
9
0
17
34
% R
% Ser:
9
0
0
9
17
0
9
50
0
0
9
9
0
0
0
% S
% Thr:
0
0
0
9
0
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
25
0
9
34
17
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _