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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HNRNPA2B1 All Species: 13.64
Human Site: T159 Identified Species: 27.27
UniProt: P22626 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22626 NP_002128.1 353 37430 T159 K R G F G F V T F D D H D P V
Chimpanzee Pan troglodytes XP_519003 614 65114 T420 K R G F G F V T F D D H D P V
Rhesus Macaque Macaca mulatta XP_001086138 320 34397 Q127 H L R D Y F D Q Y G K I E V I
Dog Lupus familis XP_864315 328 34822 R135 T I E I I T D R Q S G K K R G
Cat Felis silvestris
Mouse Mus musculus O88569 353 37384 T159 K R G F G F V T F D D H D P V
Rat Rattus norvegicus A7VJC2 353 37459 T159 K R G F G F V T F D D H D P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510026 344 36175 D150 F G F V T F D D H D P V D K I
Chicken Gallus gallus Q5ZI72 301 33425 L108 D P K R A K A L K G K E P P K
Frog Xenopus laevis P51989 346 36541 D152 F V T F D D H D P V D K I V L
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48810 385 39481 E162 K R G F A F I E F D D Y D P V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22037 346 36325 Q152 I I L D K A T Q K P R G F G F
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q99383 534 59631 D295 F V T Y D S A D A V D R V C Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 57.4 57.2 92.3 N.A. 99.7 99.7 N.A. 96.3 33.4 86.9 N.A. N.A. 44.9 N.A. 45.3 N.A.
Protein Similarity: 100 57.4 69.1 92.6 N.A. 100 99.7 N.A. 96.5 51.2 90.9 N.A. N.A. 60 N.A. 58.6 N.A.
P-Site Identity: 100 100 6.6 0 N.A. 100 100 N.A. 20 6.6 13.3 N.A. N.A. 73.3 N.A. 0 N.A.
P-Site Similarity: 100 100 26.6 0 N.A. 100 100 N.A. 26.6 6.6 20 N.A. N.A. 86.6 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 32.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 9 17 0 9 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 9 0 0 17 17 9 25 25 0 50 59 0 50 0 0 % D
% Glu: 0 0 9 0 0 0 0 9 0 0 0 9 9 0 0 % E
% Phe: 25 0 9 50 0 59 0 0 42 0 0 0 9 0 9 % F
% Gly: 0 9 42 0 34 0 0 0 0 17 9 9 0 9 9 % G
% His: 9 0 0 0 0 0 9 0 9 0 0 34 0 0 0 % H
% Ile: 9 17 0 9 9 0 9 0 0 0 0 9 9 0 17 % I
% Lys: 42 0 9 0 9 9 0 0 17 0 17 17 9 9 9 % K
% Leu: 0 9 9 0 0 0 0 9 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 9 0 0 0 0 0 0 9 9 9 0 9 50 0 % P
% Gln: 0 0 0 0 0 0 0 17 9 0 0 0 0 0 9 % Q
% Arg: 0 42 9 9 0 0 0 9 0 0 9 9 0 9 0 % R
% Ser: 0 0 0 0 0 9 0 0 0 9 0 0 0 0 0 % S
% Thr: 9 0 17 0 9 9 9 34 0 0 0 0 0 0 0 % T
% Val: 0 17 0 9 0 0 34 0 0 17 0 9 9 17 42 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 9 9 0 0 0 9 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _