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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCNO All Species: 17.88
Human Site: S32 Identified Species: 30.26
UniProt: P22674 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22674 NP_066970.3 350 38096 S32 L R A P V K K S R R P R L R R
Chimpanzee Pan troglodytes XP_517761 350 38071 S32 L R A P V K K S R R P R L R R
Rhesus Macaque Macaca mulatta XP_001098228 350 38182 S32 L R A P V K K S R R P R L Q R
Dog Lupus familis XP_544336 352 38588 S32 L R A P V K K S R R P R L R R
Cat Felis silvestris
Mouse Mus musculus P0C242 352 38803 S32 L R A P V K K S R R P C L R R
Rat Rattus norvegicus P30277 423 47373 Q54 I G N K V S E Q S R I P L K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507976 229 24720
Chicken Gallus gallus P39963 403 45933 E32 E N V P P E K E E G C Q A K R
Frog Xenopus laevis P18606 418 46754 R53 V I G D N E Q R R R S V S R G
Zebra Danio Brachydanio rerio XP_001343160 300 33697 R25 E L L C S P V R C A S D S Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999646 457 51232 A64 R V Q P S R A A K Q F R V S G
Poplar Tree Populus trichocarpa XP_002323225 450 49715 A104 V D G V A A E A R K V A V R K
Maize Zea mays NP_001140693 426 47650 A47 A P N P C A V A K K P V L Q K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P30183 428 48441 N80 K K P V V K R N A V P K P K K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 96.2 89.1 N.A. 80.1 21.7 N.A. 45.4 22.8 24.3 39.7 N.A. N.A. N.A. N.A. 24.7
Protein Similarity: 100 99.4 98 93.1 N.A. 88 39 N.A. 52.2 39.7 39.7 54 N.A. N.A. N.A. N.A. 40.7
P-Site Identity: 100 100 93.3 100 N.A. 93.3 20 N.A. 0 20 20 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 46.6 N.A. 0 40 40 6.6 N.A. N.A. N.A. N.A. 46.6
Percent
Protein Identity: 22.4 25.3 N.A. 25.4 N.A. N.A.
Protein Similarity: 34.4 38 N.A. 41.1 N.A. N.A.
P-Site Identity: 13.3 20 N.A. 20 N.A. N.A.
P-Site Similarity: 53.3 53.3 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 36 0 8 15 8 22 8 8 0 8 8 0 0 % A
% Cys: 0 0 0 8 8 0 0 0 8 0 8 8 0 0 0 % C
% Asp: 0 8 0 8 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 15 0 0 0 0 15 15 8 8 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 15 0 0 0 0 0 0 8 0 0 0 0 15 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 8 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 8 0 8 0 43 43 0 15 15 0 8 0 22 29 % K
% Leu: 36 8 8 0 0 0 0 0 0 0 0 0 50 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 15 0 8 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 8 8 58 8 8 0 0 0 0 50 8 8 0 0 % P
% Gln: 0 0 8 0 0 0 8 8 0 8 0 8 0 22 0 % Q
% Arg: 8 36 0 0 0 8 8 15 50 50 0 36 0 43 43 % R
% Ser: 0 0 0 0 15 8 0 36 8 0 15 0 15 8 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 15 8 8 15 50 0 15 0 0 8 8 15 15 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _