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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALB2
All Species:
22.73
Human Site:
S137
Identified Species:
38.46
UniProt:
P22676
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22676
NP_001731.2
271
31540
S137
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Chimpanzee
Pan troglodytes
XP_519852
276
31694
K143
E
E
L
K
N
F
L
K
D
L
L
E
K
A
N
Rhesus Macaque
Macaca mulatta
XP_001085269
274
31543
K128
E
E
L
K
N
F
L
K
D
L
L
E
K
A
N
Dog
Lupus familis
XP_853213
663
72654
S529
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Cat
Felis silvestris
Mouse
Mus musculus
Q08331
271
31354
S137
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Rat
Rattus norvegicus
P47728
271
31386
S137
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507144
434
49102
S300
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Chicken
Gallus gallus
P07090
269
31059
S135
N
E
L
K
G
F
L
S
D
L
L
K
K
A
N
Frog
Xenopus laevis
Q63ZJ3
271
31207
Q130
V
E
L
R
N
F
L
Q
D
L
F
L
Q
H
K
Zebra Danio
Brachydanio rerio
Q5XJX1
272
31560
K131
A
E
L
K
N
F
L
K
D
L
F
L
Q
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41044
310
35699
R161
D
E
L
K
N
F
L
R
D
L
L
K
E
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781517
288
33488
M137
V
N
E
L
K
S
F
M
K
H
L
I
T
K
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P41040
149
16793
D21
K
E
A
F
S
L
F
D
K
D
G
D
G
C
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Y1
157
17635
G29
R
F
D
K
N
N
D
G
K
I
S
I
D
E
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.5
54.7
39.8
N.A.
98.5
98.8
N.A.
59.4
86.3
38.7
38.9
N.A.
43.8
N.A.
N.A.
44.7
Protein Similarity:
100
71
71.1
40.1
N.A.
99.2
99.2
N.A.
61
95.5
61.6
61.4
N.A.
62.5
N.A.
N.A.
62.1
P-Site Identity:
100
73.3
73.3
100
N.A.
100
100
N.A.
100
100
40
46.6
N.A.
66.6
N.A.
N.A.
13.3
P-Site Similarity:
100
80
80
100
N.A.
100
100
N.A.
100
100
53.3
53.3
N.A.
80
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
22.5
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
35.7
N.A.
37.6
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
6.6
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
0
0
0
0
0
0
0
65
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
0
8
0
0
0
8
8
79
8
0
8
8
0
0
% D
% Glu:
15
86
8
0
0
0
0
0
0
0
0
15
8
8
0
% E
% Phe:
0
8
0
8
0
79
15
0
0
0
15
0
0
0
0
% F
% Gly:
0
0
0
0
43
0
0
8
0
0
8
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
15
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
15
0
0
8
% I
% Lys:
8
0
0
79
8
0
0
22
22
0
0
50
58
8
22
% K
% Leu:
0
0
79
8
0
8
79
0
0
79
72
15
0
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
43
8
0
0
43
8
0
0
0
0
0
0
0
0
65
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
8
0
0
0
0
15
0
0
% Q
% Arg:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
43
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% T
% Val:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _