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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALB2
All Species:
32.12
Human Site:
Y214
Identified Species:
54.36
UniProt:
P22676
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22676
NP_001731.2
271
31540
Y214
Y
D
K
D
R
S
G
Y
I
D
E
H
E
L
D
Chimpanzee
Pan troglodytes
XP_519852
276
31694
Y220
Y
D
Q
D
G
N
G
Y
I
D
E
N
E
L
D
Rhesus Macaque
Macaca mulatta
XP_001085269
274
31543
Y218
Y
D
Q
D
G
N
G
Y
I
D
E
N
E
L
D
Dog
Lupus familis
XP_853213
663
72654
Y606
Y
D
K
D
G
S
G
Y
I
D
E
N
E
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q08331
271
31354
Y214
Y
D
K
D
G
S
G
Y
I
D
E
N
E
L
D
Rat
Rattus norvegicus
P47728
271
31386
Y214
Y
D
K
D
G
S
G
Y
I
D
E
N
E
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507144
434
49102
Y377
Y
D
K
D
G
S
G
Y
I
D
E
N
E
L
D
Chicken
Gallus gallus
P07090
269
31059
F212
Y
D
K
D
G
S
G
F
I
D
E
H
E
L
D
Frog
Xenopus laevis
Q63ZJ3
271
31207
A211
Y
D
V
S
K
T
G
A
L
E
G
P
E
V
D
Zebra Danio
Brachydanio rerio
Q5XJX1
272
31560
A212
Y
D
V
S
R
T
G
A
L
E
G
P
E
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41044
310
35699
T243
Y
D
R
D
N
S
G
T
I
E
N
E
E
L
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781517
288
33488
T223
Y
D
K
D
K
N
G
T
I
E
G
D
E
L
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P41040
149
16793
F93
L
K
E
A
F
R
V
F
D
K
D
Q
N
G
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Y1
157
17635
D101
A
F
D
L
Y
D
L
D
R
N
G
R
I
S
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.5
54.7
39.8
N.A.
98.5
98.8
N.A.
59.4
86.3
38.7
38.9
N.A.
43.8
N.A.
N.A.
44.7
Protein Similarity:
100
71
71.1
40.1
N.A.
99.2
99.2
N.A.
61
95.5
61.6
61.4
N.A.
62.5
N.A.
N.A.
62.1
P-Site Identity:
100
73.3
73.3
86.6
N.A.
86.6
86.6
N.A.
86.6
86.6
33.3
40
N.A.
53.3
N.A.
N.A.
53.3
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
66.6
66.6
N.A.
66.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
22.5
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
35.7
N.A.
37.6
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
15
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
86
8
72
0
8
0
8
8
58
8
8
0
0
72
% D
% Glu:
0
0
8
0
0
0
0
0
0
29
58
8
86
0
0
% E
% Phe:
0
8
0
0
8
0
0
15
0
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
50
0
86
0
0
0
29
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
72
0
0
0
8
0
0
% I
% Lys:
0
8
50
0
15
0
0
0
0
8
0
0
0
0
8
% K
% Leu:
8
0
0
8
0
0
8
0
15
0
0
0
0
72
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
22
0
0
0
8
8
43
8
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
15
8
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
0
0
15
0
50
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% T
% Val:
0
0
15
0
0
0
8
0
0
0
0
0
0
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
86
0
0
0
8
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _