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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CALB2
All Species:
22.73
Human Site:
Y228
Identified Species:
38.46
UniProt:
P22676
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22676
NP_001731.2
271
31540
Y228
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Chimpanzee
Pan troglodytes
XP_519852
276
31694
C234
D
A
L
L
K
D
L
C
E
K
N
K
Q
D
L
Rhesus Macaque
Macaca mulatta
XP_001085269
274
31543
C232
D
A
L
L
K
D
L
C
E
K
N
K
Q
E
L
Dog
Lupus familis
XP_853213
663
72654
Y620
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Cat
Felis silvestris
Mouse
Mus musculus
Q08331
271
31354
Y228
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Rat
Rattus norvegicus
P47728
271
31386
Y228
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507144
434
49102
Y391
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Chicken
Gallus gallus
P07090
269
31059
Y226
D
A
L
L
K
D
L
Y
E
K
N
K
K
E
M
Frog
Xenopus laevis
Q63ZJ3
271
31207
M225
D
G
F
V
K
D
M
M
E
L
V
K
P
S
I
Zebra Danio
Brachydanio rerio
Q5XJX1
272
31560
M226
D
G
F
V
K
D
M
M
E
L
V
R
P
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P41044
310
35699
L257
K
G
F
L
K
D
L
L
E
L
V
K
K
D
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781517
288
33488
M237
N
G
F
L
K
D
L
M
E
H
E
G
N
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P41040
149
16793
R107
F
I
S
A
A
E
L
R
H
V
M
T
N
L
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C8Y1
157
17635
M115
A
N
E
L
H
S
V
M
K
N
L
G
E
K
C
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.5
54.7
39.8
N.A.
98.5
98.8
N.A.
59.4
86.3
38.7
38.9
N.A.
43.8
N.A.
N.A.
44.7
Protein Similarity:
100
71
71.1
40.1
N.A.
99.2
99.2
N.A.
61
95.5
61.6
61.4
N.A.
62.5
N.A.
N.A.
62.1
P-Site Identity:
100
73.3
80
100
N.A.
100
100
N.A.
100
100
33.3
26.6
N.A.
46.6
N.A.
N.A.
40
P-Site Similarity:
100
93.3
93.3
100
N.A.
100
100
N.A.
100
100
53.3
53.3
N.A.
53.3
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
22.5
N.A.
21.7
N.A.
N.A.
Protein Similarity:
N.A.
35.7
N.A.
37.6
N.A.
N.A.
P-Site Identity:
N.A.
6.6
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
58
0
8
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
8
% C
% Asp:
72
0
0
0
0
86
0
0
0
0
0
0
0
15
8
% D
% Glu:
0
0
8
0
0
8
0
0
86
0
8
0
8
58
8
% E
% Phe:
8
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
29
0
0
0
0
0
0
0
0
0
15
0
0
8
% G
% His:
0
0
0
0
8
0
0
0
8
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
15
% I
% Lys:
8
0
0
0
86
0
0
0
8
58
0
72
50
8
0
% K
% Leu:
0
0
58
79
0
0
79
8
0
22
8
0
0
8
15
% L
% Met:
0
0
0
0
0
0
15
29
0
0
8
0
0
0
43
% M
% Asn:
8
8
0
0
0
0
0
0
0
8
58
0
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% R
% Ser:
0
0
8
0
0
8
0
0
0
0
0
0
0
15
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
0
15
0
0
8
0
0
8
22
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
43
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _