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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CBL
All Species:
21.82
Human Site:
Y92
Identified Species:
43.64
UniProt:
P22681
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22681
NP_005179.2
906
99633
Y92
L
D
L
L
P
D
T
Y
Q
H
L
R
T
I
L
Chimpanzee
Pan troglodytes
XP_508878
860
94390
Q71
D
K
V
V
R
L
C
Q
N
P
K
L
A
L
K
Rhesus Macaque
Macaca mulatta
XP_001104812
907
99834
Y93
L
D
L
L
P
D
T
Y
Q
H
L
R
T
I
L
Dog
Lupus familis
XP_546487
769
85337
Cat
Felis silvestris
Mouse
Mus musculus
P22682
913
100531
Y90
L
D
L
L
P
D
T
Y
Q
H
L
R
T
V
L
Rat
Rattus norvegicus
Q8K4S7
938
104634
H84
I
L
P
D
T
Y
Q
H
L
R
L
I
L
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520299
576
65568
Chicken
Gallus gallus
NP_989539
903
99806
Y76
L
D
L
L
P
D
T
Y
Q
H
L
R
T
I
L
Frog
Xenopus laevis
Q6GQL0
918
102813
H95
I
L
P
D
T
Y
Q
H
L
R
L
I
L
S
K
Zebra Danio
Brachydanio rerio
NP_001007331
913
101156
Y76
L
D
L
L
P
D
T
Y
Q
H
L
R
T
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648224
878
94769
Y80
L
D
I
L
P
D
T
Y
Q
R
L
R
L
I
Y
Honey Bee
Apis mellifera
XP_395448
739
83094
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
98.9
70
N.A.
92.7
49.5
N.A.
52.3
84
49.6
72.2
N.A.
41.6
44.5
N.A.
N.A.
Protein Similarity:
100
94.9
99.2
72
N.A.
95
60.8
N.A.
57.6
89.4
59
80.2
N.A.
53.6
56.9
N.A.
N.A.
P-Site Identity:
100
0
100
0
N.A.
93.3
6.6
N.A.
0
100
6.6
100
N.A.
73.3
0
N.A.
N.A.
P-Site Similarity:
100
20
100
0
N.A.
100
20
N.A.
0
100
20
100
N.A.
80
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
50
0
17
0
50
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
42
0
0
0
0
0
% H
% Ile:
17
0
9
0
0
0
0
0
0
0
0
17
0
42
0
% I
% Lys:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
25
% K
% Leu:
50
17
42
50
0
9
0
0
17
0
67
9
25
9
42
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
17
0
50
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
17
9
50
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
25
0
50
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% S
% Thr:
0
0
0
0
17
0
50
0
0
0
0
0
42
0
0
% T
% Val:
0
0
9
9
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
17
0
50
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _