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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UQCRC2 All Species: 50
Human Site: S437 Identified Species: 73.33
UniProt: P22695 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22695 NP_003357.2 453 48443 S437 K F V S G Q K S M A A S G N L
Chimpanzee Pan troglodytes XP_001160709 453 48433 S437 K F V S G Q K S M A A S G N L
Rhesus Macaque Macaca mulatta XP_001092339 453 48405 S437 K F V S G Q K S M A A S G N L
Dog Lupus familis XP_536942 453 48307 S437 K F V S G R K S M A A S G N L
Cat Felis silvestris
Mouse Mus musculus Q9DB77 453 48216 S437 K F V S G K K S M A A S G N L
Rat Rattus norvegicus P32551 452 48378 S436 K F V S G K K S M T A S G N L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507390 454 48142 S438 K F V S G K K S M A A S G N L
Chicken Gallus gallus XP_424611 457 48561 S441 K F V S G K K S M A A S G D L
Frog Xenopus laevis NP_001086687 451 47842 S435 K F A S G K K S M A A T G N L
Zebra Danio Brachydanio rerio NP_001001589 454 48104 T438 K F M S G K K T M A S S G N L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625050 442 47608 S425 K L I K G K L S V A A I G N L
Nematode Worm Caenorhab. elegans P98080 471 51717 R443 I S R H V Y D R D L A A V G V
Sea Urchin Strong. purpuratus XP_001178059 453 48566 S434 R I F N G K S S M A A S G N L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9ZU25 503 54383 T482 K V I S K P L T M G S F G D V
Baker's Yeast Sacchar. cerevisiae P10507 462 51065 V439 Y R L Q N K P V S M V A L G N
Red Bread Mold Neurospora crassa P11913 476 52538 I450 K K I W D Q D I A I S A V G S
Conservation
Percent
Protein Identity: 100 99.3 96.9 88.5 N.A. 85.6 83.6 N.A. 80.6 71.1 69.7 61.2 N.A. N.A. 34.4 21.2 41.2
Protein Similarity: 100 100 97.7 92.7 N.A. 93.1 92.9 N.A. 88.1 82 82.7 77.5 N.A. N.A. 56 41.8 60.2
P-Site Identity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 93.3 86.6 80 73.3 N.A. N.A. 53.3 6.6 60
P-Site Similarity: 100 100 100 100 N.A. 100 93.3 N.A. 100 100 93.3 100 N.A. N.A. 73.3 20 80
Percent
Protein Identity: N.A. N.A. N.A. 30.2 25.7 25
Protein Similarity: N.A. N.A. N.A. 47.3 47.4 46.2
P-Site Identity: N.A. N.A. N.A. 26.6 0 13.3
P-Site Similarity: N.A. N.A. N.A. 60 20 33.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 0 0 0 7 69 75 19 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 13 0 7 0 0 0 0 13 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 63 7 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 0 0 0 75 0 0 0 0 7 0 0 82 19 0 % G
% His: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 7 19 0 0 0 0 7 0 7 0 7 0 0 0 % I
% Lys: 82 7 0 7 7 57 63 0 0 0 0 0 0 0 0 % K
% Leu: 0 7 7 0 0 0 13 0 0 7 0 0 7 0 75 % L
% Met: 0 0 7 0 0 0 0 0 75 7 0 0 0 0 0 % M
% Asn: 0 0 0 7 7 0 0 0 0 0 0 0 0 69 7 % N
% Pro: 0 0 0 0 0 7 7 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 25 0 0 0 0 0 0 0 0 0 % Q
% Arg: 7 7 7 0 0 7 0 7 0 0 0 0 0 0 0 % R
% Ser: 0 7 0 69 0 0 7 69 7 0 19 63 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 13 0 7 0 7 0 0 0 % T
% Val: 0 7 50 0 7 0 0 7 7 0 7 0 13 0 13 % V
% Trp: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _