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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGM1
All Species:
22.42
Human Site:
Y277
Identified Species:
61.67
UniProt:
P22735
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22735
NP_000350.1
817
89787
Y277
N
E
S
G
R
I
Y
Y
G
T
E
A
Q
I
G
Chimpanzee
Pan troglodytes
XP_001169470
818
89787
Y278
N
E
S
G
R
I
Y
Y
G
T
E
A
Q
I
G
Rhesus Macaque
Macaca mulatta
XP_001113577
818
89983
Y278
N
E
S
G
R
I
Y
Y
G
T
E
A
Q
I
G
Dog
Lupus familis
XP_535876
733
83369
K223
Y
G
D
F
N
D
I
K
S
R
S
W
S
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLF6
815
89807
Y276
N
E
S
G
R
I
Y
Y
G
T
E
A
Q
I
G
Rat
Rattus norvegicus
P23606
824
90751
Y285
N
E
S
G
R
I
Y
Y
G
T
E
A
Q
I
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q01841
689
77951
P179
R
D
Y
I
T
S
T
P
W
N
F
G
Q
F
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_694950
838
93314
Y323
N
D
T
G
R
I
Y
Y
G
T
E
K
Q
I
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_001154909
740
83070
N230
Y
F
Y
G
T
A
S
N
I
G
S
S
A
W
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
97.9
39
N.A.
90.9
90.4
N.A.
N.A.
30.8
N.A.
47.4
N.A.
N.A.
N.A.
N.A.
37.7
Protein Similarity:
100
99.7
98.5
55.4
N.A.
93.7
93.5
N.A.
N.A.
46.8
N.A.
63.2
N.A.
N.A.
N.A.
N.A.
53.9
P-Site Identity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
6.6
N.A.
80
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
N.A.
13.3
N.A.
93.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
56
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
12
0
0
12
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
56
0
0
0
0
0
0
0
0
67
0
0
0
12
% E
% Phe:
0
12
0
12
0
0
0
0
0
0
12
0
0
12
0
% F
% Gly:
0
12
0
78
0
0
0
0
67
12
0
12
0
0
78
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
0
67
12
0
12
0
0
0
0
67
0
% I
% Lys:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
67
0
0
0
12
0
0
12
0
12
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
78
0
0
% Q
% Arg:
12
0
0
0
67
0
0
0
0
12
0
0
0
0
0
% R
% Ser:
0
0
56
0
0
12
12
0
12
0
23
12
12
0
0
% S
% Thr:
0
0
12
0
23
0
12
0
0
67
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
12
0
0
12
0
12
0
% W
% Tyr:
23
0
23
0
0
0
67
67
0
0
0
0
0
12
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _