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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NR4A1
All Species:
15.45
Human Site:
S225
Identified Species:
30.91
UniProt:
P22736
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22736
NP_002126.2
598
64463
S225
L
G
E
G
E
S
Y
S
M
P
T
A
F
P
G
Chimpanzee
Pan troglodytes
XP_509073
802
86293
S429
L
G
E
G
E
S
Y
S
M
P
T
A
F
P
G
Rhesus Macaque
Macaca mulatta
XP_001085399
734
78645
S361
L
G
E
G
E
S
Y
S
M
P
T
A
F
P
G
Dog
Lupus familis
XP_535920
598
66603
S229
N
P
I
R
K
P
A
S
M
G
F
P
G
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
P12813
601
64720
S228
L
G
E
G
E
S
Y
S
M
P
A
A
F
P
G
Rat
Rattus norvegicus
P22829
597
64263
V225
G
E
G
E
S
Y
S
V
P
A
A
F
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508960
521
58059
Y198
D
N
A
A
C
Q
H
Y
G
V
R
T
C
E
G
Chicken
Gallus gallus
XP_422166
598
66280
R225
F
A
V
P
S
P
I
R
K
Q
P
A
M
A
F
Frog
Xenopus laevis
Q04913
577
64365
V225
P
G
V
L
D
S
S
V
L
L
D
S
P
L
S
Zebra Danio
Brachydanio rerio
NP_001002173
574
63026
L225
S
G
L
M
D
G
H
L
S
P
K
V
R
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P49869
1073
116973
N702
K
L
A
K
I
T
L
N
Q
R
H
S
H
A
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P41829
619
68604
S226
G
T
P
S
P
H
S
S
S
L
P
T
S
P
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.9
80.7
56.6
N.A.
91.3
91.4
N.A.
49.6
57
65.8
58.7
N.A.
31.2
N.A.
28.4
N.A.
Protein Similarity:
100
73.9
81
70.4
N.A.
93.8
94.1
N.A.
61.8
70.4
77.4
70.4
N.A.
40.5
N.A.
41.5
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
93.3
0
N.A.
6.6
6.6
13.3
13.3
N.A.
0
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
20
N.A.
93.3
0
N.A.
13.3
6.6
33.3
26.6
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
9
0
0
9
0
0
9
17
42
0
17
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
0
0
0
17
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
0
9
34
9
34
0
0
0
0
0
0
0
0
9
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
9
9
34
0
9
% F
% Gly:
17
50
9
34
0
9
0
0
9
9
0
0
9
9
42
% G
% His:
0
0
0
0
0
9
17
0
0
0
9
0
9
0
9
% H
% Ile:
0
0
9
0
9
0
9
0
0
0
0
0
0
0
0
% I
% Lys:
9
0
0
9
9
0
0
0
9
0
9
0
0
0
0
% K
% Leu:
34
9
9
9
0
0
9
9
9
17
0
0
0
17
9
% L
% Met:
0
0
0
9
0
0
0
0
42
0
0
0
9
0
0
% M
% Asn:
9
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% N
% Pro:
9
9
9
9
9
17
0
0
9
42
17
9
17
42
17
% P
% Gln:
0
0
0
0
0
9
0
0
9
9
0
0
0
0
9
% Q
% Arg:
0
0
0
9
0
0
0
9
0
9
9
0
9
0
0
% R
% Ser:
9
0
0
9
17
42
25
50
17
0
0
17
9
9
9
% S
% Thr:
0
9
0
0
0
9
0
0
0
0
25
17
0
0
0
% T
% Val:
0
0
17
0
0
0
0
17
0
9
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
34
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _