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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
25.45
Human Site:
S129
Identified Species:
56
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S129
P
Y
K
G
S
E
H
S
L
D
G
E
H
F
A
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S129
P
Y
K
G
S
E
H
S
L
D
G
E
H
F
A
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
S237
L
D
K
G
S
E
H
S
L
D
G
E
H
F
A
Dog
Lupus familis
XP_537711
336
37808
T153
M
D
G
G
S
E
H
T
I
N
G
N
R
F
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
S128
N
D
N
G
S
E
H
S
I
D
G
R
H
F
A
Rat
Rattus norvegicus
P48284
309
35058
S128
S
N
K
G
S
E
H
S
I
D
G
K
H
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
F132
V
Q
E
E
Q
L
Y
F
P
G
S
E
H
S
I
Frog
Xenopus laevis
NP_001121289
301
33404
T132
E
F
H
G
S
E
H
T
I
D
G
E
K
F
P
Zebra Danio
Brachydanio rerio
Q92051
260
28659
F114
H
T
I
A
G
T
K
F
P
C
E
L
H
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
A131
D
A
V
G
S
E
H
A
M
G
S
L
H
Y
P
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
T136
D
M
K
G
S
E
H
T
V
D
G
K
R
Y
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
86.6
46.6
N.A.
66.6
73.3
N.A.
N.A.
13.3
53.3
6.6
N.A.
N.A.
N.A.
33.3
46.6
P-Site Similarity:
100
100
86.6
66.6
N.A.
73.3
86.6
N.A.
N.A.
26.6
73.3
6.6
N.A.
N.A.
N.A.
53.3
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
10
0
0
0
0
0
0
55
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
19
28
0
0
0
0
0
0
0
64
0
0
0
0
0
% D
% Glu:
10
0
10
10
0
82
0
0
0
0
10
46
0
0
0
% E
% Phe:
0
10
0
0
0
0
0
19
0
0
0
0
0
64
0
% F
% Gly:
0
0
10
82
10
0
0
0
0
19
73
0
0
0
0
% G
% His:
10
0
10
0
0
0
82
0
0
0
0
0
73
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
37
0
0
0
0
0
10
% I
% Lys:
0
0
46
0
0
0
10
0
0
0
0
19
10
0
0
% K
% Leu:
10
0
0
0
0
10
0
0
28
0
0
19
0
10
0
% L
% Met:
10
10
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
10
10
10
0
0
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
19
0
0
0
0
0
0
0
19
0
0
0
0
0
28
% P
% Gln:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% R
% Ser:
10
0
0
0
82
0
0
46
0
0
19
0
0
10
0
% S
% Thr:
0
10
0
0
0
10
0
28
0
0
0
0
0
0
0
% T
% Val:
10
0
10
0
0
0
0
0
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
10
0
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _