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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
14.24
Human Site:
S18
Identified Species:
31.33
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S18
S
A
A
R
P
S
A
S
A
E
S
H
W
C
Y
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S18
S
A
A
R
P
S
A
S
A
E
S
H
W
C
Y
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
A126
S
A
A
R
P
S
A
A
A
E
S
H
W
C
Y
Dog
Lupus familis
XP_537711
336
37808
S42
E
E
N
I
K
A
N
S
W
E
S
H
W
C
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
T17
L
A
Y
V
A
P
S
T
E
D
S
G
W
C
Y
Rat
Rattus norvegicus
P48284
309
35058
T17
L
A
Y
V
A
P
S
T
E
D
S
H
W
C
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
E17
S
L
H
I
L
K
T
E
A
V
V
G
Q
H
W
Frog
Xenopus laevis
NP_001121289
301
33404
A19
L
S
F
I
K
N
S
A
A
A
G
N
W
C
Y
Zebra Danio
Brachydanio rerio
Q92051
260
28659
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
S19
V
A
L
L
V
V
V
S
C
G
P
G
S
D
H
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
T24
G
P
A
L
A
V
I
T
I
D
N
W
S
Y
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
93.3
46.6
N.A.
33.3
40
N.A.
N.A.
13.3
26.6
0
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
53.3
N.A.
53.3
60
N.A.
N.A.
20
60
0
N.A.
N.A.
N.A.
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
55
37
0
28
10
28
19
46
10
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
64
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
28
0
0
0
10
0
% D
% Glu:
10
10
0
0
0
0
0
10
19
37
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
0
0
0
0
0
10
10
28
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
46
0
10
10
% H
% Ile:
0
0
0
28
0
0
10
0
10
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
19
10
0
0
0
0
0
0
0
0
0
% K
% Leu:
28
10
10
19
10
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
10
10
0
0
0
10
10
0
0
0
% N
% Pro:
0
10
0
0
28
19
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
37
10
0
0
0
28
28
37
0
0
55
0
19
0
0
% S
% Thr:
0
0
0
0
0
0
10
28
0
0
0
0
0
0
0
% T
% Val:
10
0
0
19
10
19
10
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
10
64
0
10
% W
% Tyr:
0
0
19
0
0
0
0
0
0
0
0
0
0
10
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _