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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
13.03
Human Site:
S188
Identified Species:
28.67
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S188
Q
P
L
V
E
A
L
S
N
I
P
K
P
E
M
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S188
Q
P
L
V
E
A
L
S
D
I
P
K
P
E
M
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
S296
R
P
L
V
E
A
L
S
N
I
P
K
P
E
M
Dog
Lupus familis
XP_537711
336
37808
S212
P
L
V
D
T
L
S
S
V
P
R
P
K
M
N
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
P181
Q
P
L
V
E
A
L
P
S
I
S
K
P
H
S
Rat
Rattus norvegicus
P48284
309
35058
S185
Q
P
L
V
E
A
L
S
R
L
S
K
P
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
D194
A
T
L
I
S
E
L
D
N
I
P
Q
K
D
T
Frog
Xenopus laevis
NP_001121289
301
33404
I182
Y
D
S
L
I
K
S
I
E
A
I
T
A
V
D
Zebra Danio
Brachydanio rerio
Q92051
260
28659
V159
A
N
P
R
L
Q
K
V
L
D
A
L
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
R186
K
F
S
P
I
S
E
R
L
H
D
L
R
H
S
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
D191
A
L
I
L
K
V
P
D
A
I
I
L
V
K
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
93.3
93.3
6.6
N.A.
66.6
66.6
N.A.
N.A.
33.3
0
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
100
100
13.3
N.A.
73.3
73.3
N.A.
N.A.
53.3
6.6
13.3
N.A.
N.A.
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
28
0
0
0
0
46
0
0
10
10
10
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
10
0
0
0
19
10
10
10
0
10
19
10
% D
% Glu:
0
0
0
0
46
10
10
0
10
0
0
0
0
28
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
19
0
% H
% Ile:
0
0
10
10
19
0
0
10
0
55
19
0
0
0
10
% I
% Lys:
10
0
0
0
10
10
10
0
0
0
0
46
19
10
0
% K
% Leu:
0
19
55
19
10
10
55
0
19
10
0
28
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
28
% M
% Asn:
0
10
0
0
0
0
0
0
28
0
0
0
0
0
10
% N
% Pro:
10
46
10
10
0
0
10
10
0
10
37
10
46
0
10
% P
% Gln:
37
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
0
10
0
0
0
10
10
0
10
0
10
0
0
% R
% Ser:
0
0
19
0
10
10
19
46
10
0
19
0
0
0
19
% S
% Thr:
0
10
0
0
10
0
0
0
0
0
0
10
0
0
19
% T
% Val:
0
0
10
46
0
10
0
10
10
0
0
0
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _