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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
10.91
Human Site:
S196
Identified Species:
24
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S196
N
I
P
K
P
E
M
S
T
T
M
A
E
S
S
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S196
D
I
P
K
P
E
M
S
T
M
M
A
E
S
S
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
N304
N
I
P
K
P
E
M
N
T
T
M
A
E
S
S
Dog
Lupus familis
XP_537711
336
37808
T220
V
P
R
P
K
M
N
T
T
M
K
E
S
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
T189
S
I
S
K
P
H
S
T
S
T
V
R
E
S
S
Rat
Rattus norvegicus
P48284
309
35058
N193
R
L
S
K
P
F
T
N
S
T
V
S
E
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
S202
N
I
P
Q
K
D
T
S
S
W
M
E
P
L
P
Frog
Xenopus laevis
NP_001121289
301
33404
G190
E
A
I
T
A
V
D
G
I
K
N
F
S
A
N
Zebra Danio
Brachydanio rerio
Q92051
260
28659
K167
L
D
A
L
D
D
I
K
S
K
G
R
Q
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
G194
L
H
D
L
R
H
S
G
N
K
T
E
L
K
N
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
H199
A
I
I
L
V
K
P
H
T
H
Q
E
M
E
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
86.6
93.3
13.3
N.A.
46.6
33.3
N.A.
N.A.
33.3
0
0
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
100
93.3
100
20
N.A.
73.3
66.6
N.A.
N.A.
53.3
13.3
40
N.A.
N.A.
N.A.
6.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
10
0
0
0
0
0
0
28
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
10
0
10
19
10
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
28
0
0
0
0
0
37
46
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
19
0
0
10
0
0
0
0
% G
% His:
0
10
0
0
0
19
0
10
0
10
0
0
0
0
0
% H
% Ile:
0
55
19
0
0
0
10
0
10
0
0
0
0
10
0
% I
% Lys:
0
0
0
46
19
10
0
10
0
28
10
0
0
10
0
% K
% Leu:
19
10
0
28
0
0
0
0
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
10
28
0
0
19
37
0
10
0
0
% M
% Asn:
28
0
0
0
0
0
10
19
10
0
10
0
0
0
28
% N
% Pro:
0
10
37
10
46
0
10
0
0
0
0
0
10
0
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% Q
% Arg:
10
0
10
0
10
0
0
0
0
0
0
19
0
0
0
% R
% Ser:
10
0
19
0
0
0
19
28
37
0
0
10
19
46
46
% S
% Thr:
0
0
0
10
0
0
19
19
46
37
10
0
0
10
10
% T
% Val:
10
0
0
0
10
10
0
0
0
0
19
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _