KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
20.91
Human Site:
S284
Identified Species:
46
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S284
G
Q
R
T
V
I
K
S
G
A
P
G
R
P
L
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S284
G
Q
R
T
V
I
K
S
G
A
P
G
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
S392
G
Q
R
V
V
L
R
S
G
A
P
G
Q
L
L
Dog
Lupus familis
XP_537711
336
37808
S308
G
Q
R
V
V
F
K
S
Q
A
P
G
Q
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
S277
G
K
R
Q
V
F
K
S
H
A
P
G
Q
L
L
Rat
Rattus norvegicus
P48284
309
35058
S281
G
N
R
Q
V
F
R
S
H
A
S
G
R
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
S289
N
G
R
S
V
Y
W
S
S
A
S
S
L
L
P
Frog
Xenopus laevis
NP_001121289
301
33404
S276
G
N
R
I
V
Y
T
S
S
S
Q
V
I
V
S
Zebra Danio
Brachydanio rerio
Q92051
260
28659
R253
P
P
Q
P
L
K
G
R
K
V
R
A
S
F
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
P280
G
R
R
I
Q
Y
R
P
S
K
L
D
R
A
M
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
V290
G
T
R
T
V
Y
A
V
T
V
E
G
G
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
66.6
66.6
N.A.
60
53.3
N.A.
N.A.
26.6
26.6
0
N.A.
N.A.
N.A.
20
40
P-Site Similarity:
100
100
86.6
73.3
N.A.
73.3
60
N.A.
N.A.
33.3
33.3
13.3
N.A.
N.A.
N.A.
40
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
64
0
10
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
0
28
0
0
0
0
0
0
0
10
0
% F
% Gly:
82
10
0
0
0
0
10
0
28
0
0
64
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
19
0
0
0
0
0
0
% H
% Ile:
0
0
0
19
0
19
0
0
0
0
0
0
10
0
0
% I
% Lys:
0
10
0
0
0
10
37
0
10
10
0
0
0
0
10
% K
% Leu:
0
0
0
0
10
10
0
0
0
0
10
0
10
46
55
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
19
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
10
0
0
0
10
0
0
46
0
0
28
10
% P
% Gln:
0
37
10
19
10
0
0
0
10
0
10
0
28
0
0
% Q
% Arg:
0
10
91
0
0
0
28
10
0
0
10
0
37
0
0
% R
% Ser:
0
0
0
10
0
0
0
73
28
10
19
10
10
0
10
% S
% Thr:
0
10
0
28
0
0
10
0
10
0
0
0
0
0
10
% T
% Val:
0
0
0
19
82
0
0
10
0
19
0
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _