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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
24.55
Human Site:
S52
Identified Species:
54
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
S52
N
C
Q
K
D
R
Q
S
P
I
N
I
V
T
T
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
S52
N
C
Q
K
D
R
Q
S
P
I
N
I
V
T
T
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
S160
N
C
Q
K
D
R
Q
S
P
I
N
I
V
T
R
Dog
Lupus familis
XP_537711
336
37808
S76
D
C
Q
K
S
R
Q
S
P
I
N
I
D
T
T
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
S51
A
C
K
E
N
Q
Q
S
P
I
N
I
V
T
A
Rat
Rattus norvegicus
P48284
309
35058
S51
D
C
K
K
N
Q
Q
S
P
I
N
I
V
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
S55
K
C
K
G
S
K
Q
S
P
I
N
I
V
T
K
Frog
Xenopus laevis
NP_001121289
301
33404
N55
G
Q
Q
Q
S
P
I
N
I
H
T
K
G
A
V
Zebra Danio
Brachydanio rerio
Q92051
260
28659
Q37
P
I
D
I
V
P
T
Q
A
Q
H
D
P
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
I54
L
K
Q
S
P
I
D
I
R
A
P
D
V
D
Y
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
I59
S
S
Q
S
P
I
N
I
D
T
K
K
T
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
93.3
80
N.A.
60
66.6
N.A.
N.A.
60
6.6
0
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
93.3
86.6
N.A.
86.6
100
N.A.
N.A.
73.3
20
13.3
N.A.
N.A.
N.A.
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
10
10
0
0
0
10
10
% A
% Cys:
0
64
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
19
0
10
0
28
0
10
0
10
0
0
19
10
10
10
% D
% Glu:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
10
0
10
0
19
10
19
10
64
0
64
0
0
0
% I
% Lys:
10
10
28
46
0
10
0
0
0
0
10
19
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
28
0
0
0
19
0
10
10
0
0
64
0
0
0
0
% N
% Pro:
10
0
0
0
19
19
0
0
64
0
10
0
10
0
0
% P
% Gln:
0
10
64
10
0
19
64
10
0
10
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
37
0
0
10
0
0
0
0
0
10
% R
% Ser:
10
10
0
19
28
0
0
64
0
0
0
0
0
19
10
% S
% Thr:
0
0
0
0
0
0
10
0
0
10
10
0
10
64
28
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
64
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _