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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CA4 All Species: 14.24
Human Site: S73 Identified Species: 31.33
UniProt: P22748 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22748 NP_000708.1 312 35032 S73 K L G R F F F S G Y D K K Q T
Chimpanzee Pan troglodytes XP_001140977 312 35047 S73 K L G R F F F S G Y D K K Q T
Rhesus Macaque Macaca mulatta XP_001107970 420 45906 S181 K L G R F S F S G Y D K K Q T
Dog Lupus familis XP_537711 336 37808 S97 N L G P F S F S G Y D K K Q Q
Cat Felis silvestris
Mouse Mus musculus Q64444 305 34333 V72 R L T P F I L V G Y D Q K Q Q
Rat Rattus norvegicus P48284 309 35058 V72 S L T P F T F V G Y D Q K K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415893 316 36141 E76 N L T P L H F E N Y D V K G S
Frog Xenopus laevis NP_001121289 301 33404 G76 L V Q F N L T G Y G D I V R K
Zebra Danio Brachydanio rerio Q92051 260 28659 S58 Y D P A T T K S I L N N G H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10462 310 34843 D75 H F L N Y D M D G K I E L S N
Sea Urchin Strong. purpuratus XP_781482 303 33106 T80 N L Q S Y D T T K P V T I E N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 64 64.8 N.A. 56.7 58.3 N.A. N.A. 40.1 34.9 31.4 N.A. N.A. N.A. 31 30.7
Protein Similarity: 100 99.3 68.3 77.6 N.A. 72.7 74.6 N.A. N.A. 55 53.8 44.8 N.A. N.A. N.A. 45.1 46.4
P-Site Identity: 100 100 93.3 73.3 N.A. 46.6 46.6 N.A. N.A. 33.3 6.6 6.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 93.3 73.3 N.A. 60 60 N.A. N.A. 40 20 20 N.A. N.A. N.A. 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 19 0 10 0 0 73 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 10 0 10 0 % E
% Phe: 0 10 0 10 55 19 55 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 37 0 0 0 0 10 64 10 0 0 10 10 0 % G
% His: 10 0 0 0 0 10 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 0 0 0 0 10 0 0 10 0 10 10 10 0 0 % I
% Lys: 28 0 0 0 0 0 10 0 10 10 0 37 64 10 19 % K
% Leu: 10 73 10 0 10 10 10 0 0 10 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 28 0 0 10 10 0 0 0 10 0 10 10 0 0 19 % N
% Pro: 0 0 10 37 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 19 0 0 0 0 0 0 0 0 19 0 46 19 % Q
% Arg: 10 0 0 28 0 0 0 0 0 0 0 0 0 10 0 % R
% Ser: 10 0 0 10 0 19 0 46 0 0 0 0 0 10 19 % S
% Thr: 0 0 28 0 10 19 19 10 0 0 0 10 0 0 28 % T
% Val: 0 10 0 0 0 0 0 19 0 0 10 10 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 19 0 0 0 10 64 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _