KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
10.61
Human Site:
T198
Identified Species:
23.33
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
T198
P
K
P
E
M
S
T
T
M
A
E
S
S
L
L
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
M198
P
K
P
E
M
S
T
M
M
A
E
S
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
T306
P
K
P
E
M
N
T
T
M
A
E
S
S
L
L
Dog
Lupus familis
XP_537711
336
37808
M222
R
P
K
M
N
T
T
M
K
E
S
I
S
L
F
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
T191
S
K
P
H
S
T
S
T
V
R
E
S
S
L
Q
Rat
Rattus norvegicus
P48284
309
35058
T195
S
K
P
F
T
N
S
T
V
S
E
S
C
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
W204
P
Q
K
D
T
S
S
W
M
E
P
L
P
L
N
Frog
Xenopus laevis
NP_001121289
301
33404
K192
I
T
A
V
D
G
I
K
N
F
S
A
N
L
A
Zebra Danio
Brachydanio rerio
Q92051
260
28659
K169
A
L
D
D
I
K
S
K
G
R
Q
T
T
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
K196
D
L
R
H
S
G
N
K
T
E
L
K
N
F
R
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
H201
I
L
V
K
P
H
T
H
Q
E
M
E
N
F
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
93.3
93.3
20
N.A.
46.6
40
N.A.
N.A.
26.6
6.6
0
N.A.
N.A.
N.A.
0
6.6
P-Site Similarity:
100
93.3
100
26.6
N.A.
66.6
66.6
N.A.
N.A.
46.6
20
40
N.A.
N.A.
N.A.
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
0
0
0
28
0
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% C
% Asp:
10
0
10
19
10
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
28
0
0
0
0
0
37
46
10
0
0
0
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
28
10
% F
% Gly:
0
0
0
0
0
19
0
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
19
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
19
0
0
0
10
0
10
0
0
0
0
10
0
0
0
% I
% Lys:
0
46
19
10
0
10
0
28
10
0
0
10
0
0
0
% K
% Leu:
0
28
0
0
0
0
0
0
0
0
10
10
0
73
28
% L
% Met:
0
0
0
10
28
0
0
19
37
0
10
0
0
0
0
% M
% Asn:
0
0
0
0
10
19
10
0
10
0
0
0
28
0
10
% N
% Pro:
37
10
46
0
10
0
0
0
0
0
10
0
10
0
0
% P
% Gln:
0
10
0
0
0
0
0
0
10
0
10
0
0
0
19
% Q
% Arg:
10
0
10
0
0
0
0
0
0
19
0
0
0
0
10
% R
% Ser:
19
0
0
0
19
28
37
0
0
10
19
46
46
0
0
% S
% Thr:
0
10
0
0
19
19
46
37
10
0
0
10
10
0
10
% T
% Val:
0
0
10
10
0
0
0
0
19
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _