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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
8.79
Human Site:
T280
Identified Species:
19.33
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
T280
L
Q
Q
L
G
Q
R
T
V
I
K
S
G
A
P
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
T280
L
Q
Q
L
G
Q
R
T
V
I
K
S
G
A
P
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
V388
L
Q
R
P
G
Q
R
V
V
L
R
S
G
A
P
Dog
Lupus familis
XP_537711
336
37808
V304
L
Q
R
Q
G
Q
R
V
V
F
K
S
Q
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
Q273
L
Q
P
L
G
K
R
Q
V
F
K
S
H
A
P
Rat
Rattus norvegicus
P48284
309
35058
Q277
L
Q
P
L
G
N
R
Q
V
F
R
S
H
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
S285
A
Q
F
L
N
G
R
S
V
Y
W
S
S
A
S
Frog
Xenopus laevis
NP_001121289
301
33404
I272
V
Q
K
R
G
N
R
I
V
Y
T
S
S
S
Q
Zebra Danio
Brachydanio rerio
Q92051
260
28659
P249
D
N
Y
R
P
P
Q
P
L
K
G
R
K
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
I276
Q
P
L
N
G
R
R
I
Q
Y
R
P
S
K
L
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
T286
L
Q
S
L
G
T
R
T
V
Y
A
V
T
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
66.6
66.6
N.A.
66.6
53.3
N.A.
N.A.
40
33.3
0
N.A.
N.A.
N.A.
13.3
46.6
P-Site Similarity:
100
100
86.6
73.3
N.A.
73.3
60
N.A.
N.A.
46.6
53.3
13.3
N.A.
N.A.
N.A.
26.6
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
10
0
0
64
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
28
0
0
0
0
0
% F
% Gly:
0
0
0
0
82
10
0
0
0
0
10
0
28
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% H
% Ile:
0
0
0
0
0
0
0
19
0
19
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
10
37
0
10
10
0
% K
% Leu:
64
0
10
55
0
0
0
0
10
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
19
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
19
10
10
10
0
10
0
0
0
10
0
0
46
% P
% Gln:
10
82
19
10
0
37
10
19
10
0
0
0
10
0
10
% Q
% Arg:
0
0
19
19
0
10
91
0
0
0
28
10
0
0
10
% R
% Ser:
0
0
10
0
0
0
0
10
0
0
0
73
28
10
19
% S
% Thr:
0
0
0
0
0
10
0
28
0
0
10
0
10
0
0
% T
% Val:
10
0
0
0
0
0
0
19
82
0
0
10
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
37
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _