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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
12.12
Human Site:
T80
Identified Species:
26.67
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
T80
S
G
Y
D
K
K
Q
T
W
T
V
Q
N
N
G
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
T80
S
G
Y
D
K
K
Q
T
W
T
V
Q
N
N
G
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
T188
S
G
Y
D
K
K
Q
T
W
T
V
Q
N
N
G
Dog
Lupus familis
XP_537711
336
37808
Q104
S
G
Y
D
K
K
Q
Q
W
R
V
Q
N
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
Q79
V
G
Y
D
Q
K
Q
Q
W
P
I
K
N
N
Q
Rat
Rattus norvegicus
P48284
309
35058
K79
V
G
Y
D
Q
K
K
K
W
E
V
K
N
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
S83
E
N
Y
D
V
K
G
S
S
K
W
K
I
E
N
Frog
Xenopus laevis
NP_001121289
301
33404
K83
G
Y
G
D
I
V
R
K
L
S
I
T
N
N
G
Zebra Danio
Brachydanio rerio
Q92051
260
28659
S65
S
I
L
N
N
G
H
S
F
Q
V
D
F
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
N82
D
G
K
I
E
L
S
N
T
G
R
T
L
F
A
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
N87
T
K
P
V
T
I
E
N
N
G
H
A
L
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
100
86.6
N.A.
53.3
53.3
N.A.
N.A.
20
26.6
13.3
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
73.3
N.A.
N.A.
33.3
46.6
33.3
N.A.
N.A.
N.A.
13.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
73
0
0
0
0
0
0
0
10
0
0
10
% D
% Glu:
10
0
0
0
10
0
10
0
0
10
0
0
0
19
0
% E
% Phe:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% F
% Gly:
10
64
10
0
0
10
10
0
0
19
0
0
0
0
46
% G
% His:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% H
% Ile:
0
10
0
10
10
10
0
0
0
0
19
0
10
0
0
% I
% Lys:
0
10
10
0
37
64
10
19
0
10
0
28
0
0
0
% K
% Leu:
0
0
10
0
0
10
0
0
10
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
10
10
0
0
19
10
0
0
0
64
64
10
% N
% Pro:
0
0
10
0
0
0
0
0
0
10
0
0
0
0
0
% P
% Gln:
0
0
0
0
19
0
46
19
0
10
0
37
0
0
19
% Q
% Arg:
0
0
0
0
0
0
10
0
0
10
10
0
0
0
0
% R
% Ser:
46
0
0
0
0
0
10
19
10
10
0
0
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
28
10
28
0
19
0
0
0
% T
% Val:
19
0
0
10
10
10
0
0
0
0
55
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
55
0
10
0
0
0
0
% W
% Tyr:
0
10
64
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _