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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
34.55
Human Site:
Y220
Identified Species:
76
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
Y220
K
L
R
H
Y
F
R
Y
L
G
S
L
T
T
P
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
Y220
K
L
R
H
Y
F
R
Y
L
G
S
L
T
T
P
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
Y328
K
L
R
N
Y
F
R
Y
L
G
S
L
T
T
P
Dog
Lupus familis
XP_537711
336
37808
Y244
K
L
R
H
Y
Y
R
Y
L
G
S
L
T
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
Y213
K
M
Y
T
Y
F
R
Y
N
G
S
L
T
T
P
Rat
Rattus norvegicus
P48284
309
35058
Y217
K
L
S
A
Y
F
R
Y
Q
G
S
L
T
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
Y226
E
L
E
K
Y
Y
R
Y
E
G
S
L
T
T
P
Frog
Xenopus laevis
NP_001121289
301
33404
Y214
A
L
K
L
Y
Y
R
Y
N
G
S
L
T
T
P
Zebra Danio
Brachydanio rerio
Q92051
260
28659
W191
L
P
A
S
L
D
Y
W
T
Y
E
G
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
Y218
D
T
E
A
F
Y
R
Y
E
G
S
L
T
T
P
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
Y223
S
L
D
K
F
W
R
Y
D
G
S
L
T
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
93.3
93.3
N.A.
73.3
80
N.A.
N.A.
66.6
66.6
0
N.A.
N.A.
N.A.
53.3
60
P-Site Similarity:
100
100
100
100
N.A.
80
80
N.A.
N.A.
80
80
13.3
N.A.
N.A.
N.A.
66.6
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
10
0
0
10
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
19
0
0
0
0
0
19
0
10
0
0
0
0
% E
% Phe:
0
0
0
0
19
46
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
91
0
10
0
0
0
% G
% His:
0
0
0
28
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
55
0
10
19
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
73
0
10
10
0
0
0
37
0
0
91
0
10
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
0
19
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
91
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
0
37
0
0
0
91
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
10
0
0
0
0
0
0
91
0
10
0
0
% S
% Thr:
0
10
0
10
0
0
0
0
10
0
0
0
91
91
10
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
73
37
10
91
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _