Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CA4 All Species: 22.42
Human Site: Y25 Identified Species: 49.33
UniProt: P22748 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P22748 NP_000708.1 312 35032 Y25 S A E S H W C Y E V Q A E S S
Chimpanzee Pan troglodytes XP_001140977 312 35047 Y25 S A E S H W C Y E V Q A E S S
Rhesus Macaque Macaca mulatta XP_001107970 420 45906 Y133 A A E S H W C Y E S Q A N S S
Dog Lupus familis XP_537711 336 37808 Y49 S W E S H W C Y E I Q A K A S
Cat Felis silvestris
Mouse Mus musculus Q64444 305 34333 Y24 T E D S G W C Y E I Q T K D P
Rat Rattus norvegicus P48284 309 35058 Y24 T E D S H W C Y E I Q A K E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415893 316 36141 W24 E A V V G Q H W C Y L S Q K N
Frog Xenopus laevis NP_001121289 301 33404 Y26 A A A G N W C Y E I Q G C A G
Zebra Danio Brachydanio rerio Q92051 260 28659 P13 G Y G P A D G P E S W A E S F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q10462 310 34843 H26 S C G P G S D H G W G Y D E N
Sea Urchin Strong. purpuratus XP_781482 303 33106 A31 T I D N W S Y A G A G D T D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 64 64.8 N.A. 56.7 58.3 N.A. N.A. 40.1 34.9 31.4 N.A. N.A. N.A. 31 30.7
Protein Similarity: 100 99.3 68.3 77.6 N.A. 72.7 74.6 N.A. N.A. 55 53.8 44.8 N.A. N.A. N.A. 45.1 46.4
P-Site Identity: 100 100 80 73.3 N.A. 40 53.3 N.A. N.A. 6.6 40 26.6 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 86.6 93.3 N.A. 66.6 80 N.A. N.A. 33.3 66.6 26.6 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 46 10 0 10 0 0 10 0 10 0 55 0 19 0 % A
% Cys: 0 10 0 0 0 0 64 0 10 0 0 0 10 0 0 % C
% Asp: 0 0 28 0 0 10 10 0 0 0 0 10 10 19 0 % D
% Glu: 10 19 37 0 0 0 0 0 73 0 0 0 28 19 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % F
% Gly: 10 0 19 10 28 0 10 0 19 0 19 10 0 0 10 % G
% His: 0 0 0 0 46 0 10 10 0 0 0 0 0 0 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 37 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 28 10 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 10 10 0 0 0 0 0 0 0 10 0 19 % N
% Pro: 0 0 0 19 0 0 0 10 0 0 0 0 0 0 19 % P
% Gln: 0 0 0 0 0 10 0 0 0 0 64 0 10 0 10 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 37 0 0 55 0 19 0 0 0 19 0 10 0 37 37 % S
% Thr: 28 0 0 0 0 0 0 0 0 0 0 10 10 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 19 0 0 0 0 0 % V
% Trp: 0 10 0 0 10 64 0 10 0 10 10 0 0 0 0 % W
% Tyr: 0 10 0 0 0 0 10 64 0 10 0 10 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _