KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CA4
All Species:
18.79
Human Site:
Y75
Identified Species:
41.33
UniProt:
P22748
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P22748
NP_000708.1
312
35032
Y75
G
R
F
F
F
S
G
Y
D
K
K
Q
T
W
T
Chimpanzee
Pan troglodytes
XP_001140977
312
35047
Y75
G
R
F
F
F
S
G
Y
D
K
K
Q
T
W
T
Rhesus Macaque
Macaca mulatta
XP_001107970
420
45906
Y183
G
R
F
S
F
S
G
Y
D
K
K
Q
T
W
T
Dog
Lupus familis
XP_537711
336
37808
Y99
G
P
F
S
F
S
G
Y
D
K
K
Q
Q
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Q64444
305
34333
Y74
T
P
F
I
L
V
G
Y
D
Q
K
Q
Q
W
P
Rat
Rattus norvegicus
P48284
309
35058
Y74
T
P
F
T
F
V
G
Y
D
Q
K
K
K
W
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415893
316
36141
Y78
T
P
L
H
F
E
N
Y
D
V
K
G
S
S
K
Frog
Xenopus laevis
NP_001121289
301
33404
G78
Q
F
N
L
T
G
Y
G
D
I
V
R
K
L
S
Zebra Danio
Brachydanio rerio
Q92051
260
28659
L60
P
A
T
T
K
S
I
L
N
N
G
H
S
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q10462
310
34843
K77
L
N
Y
D
M
D
G
K
I
E
L
S
N
T
G
Sea Urchin
Strong. purpuratus
XP_781482
303
33106
P82
Q
S
Y
D
T
T
K
P
V
T
I
E
N
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
64
64.8
N.A.
56.7
58.3
N.A.
N.A.
40.1
34.9
31.4
N.A.
N.A.
N.A.
31
30.7
Protein Similarity:
100
99.3
68.3
77.6
N.A.
72.7
74.6
N.A.
N.A.
55
53.8
44.8
N.A.
N.A.
N.A.
45.1
46.4
P-Site Identity:
100
100
93.3
73.3
N.A.
46.6
46.6
N.A.
N.A.
26.6
6.6
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
53.3
60
N.A.
N.A.
33.3
20
26.6
N.A.
N.A.
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
19
0
10
0
0
73
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
10
0
10
0
0
10
% E
% Phe:
0
10
55
19
55
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
37
0
0
0
0
10
64
10
0
0
10
10
0
0
19
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
10
10
10
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
10
10
0
37
64
10
19
0
10
% K
% Leu:
10
0
10
10
10
0
0
10
0
0
10
0
0
10
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
10
0
10
10
0
0
19
10
0
% N
% Pro:
10
37
0
0
0
0
0
10
0
0
0
0
0
0
10
% P
% Gln:
19
0
0
0
0
0
0
0
0
19
0
46
19
0
10
% Q
% Arg:
0
28
0
0
0
0
0
0
0
0
0
10
0
0
10
% R
% Ser:
0
10
0
19
0
46
0
0
0
0
0
10
19
10
10
% S
% Thr:
28
0
10
19
19
10
0
0
0
10
0
0
28
10
28
% T
% Val:
0
0
0
0
0
19
0
0
10
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
55
0
% W
% Tyr:
0
0
19
0
0
0
10
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _